Research Achievements

I. Publications (*corresponding author)

2018

  1. Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, Li H, Wu JY, Dorajoo R, Nierenberg JL, Wang YX, He J, Bennett DA, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Rakugi H, Nakashima  E, Isono M, Shirota M, Hozawa A, Ichihara S, Matsubara T, Yamamoto K, Kohara K, Igase M, Han S, Gordon-Larsen P, Huang W, Lee NR, Adair LS, Hwang MY, Lee J, Chee ML, Sabanayagam C, Zhao W, Liu J, Reilly DF, Sun L, Huo S, Edwards TL, Long J, Chang LC, Chen CH, Yuan JM, Koh WP, Friedlander Y, Kelly TN, Bin Wei W, Xu L, Cai H, Xiang YB, Lin K, Clarke R, Walters RG, Millwood IY, Li L, Chambers JC, Kooner JS, Elliott P, van der Harst P; International Genomics of Blood Pressure (iGEN-BP) Consortium, Chen Z, Sasaki M, Shu XO, Jonas JB, He J, Heng CK, Chen YT, Zheng W, Lin X, Teo YY, Tai ES, Cheng CY, Wong TY, Sim X, Mohlke KL, Yamamoto M, Kim BJ, Miki T, Nabika T, Yokota M, Kamatani Y, Kubo M, Kato N*. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nat Commun. 2018 Nov 28;9(1):5052. PMID: 30487518
  2. Niiya K, Ohara H, Isono M, Sheikh AM, Matsuo H, Fujikawa K, Isomura M, Kato N, Nabika T. Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat. Sci Rep. 2018 Jun 20;8(1):9403. PMID: 29925869
  3. Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, Brown MR, Schwander K, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Wojczynski MK, Alver M, Boissel M, Cai Q, Campbell A, Chai JF, Chen X, Divers J, Gao C, Goel A, Hagemeijer Y, Harris SE, He M, Hsu FC, Jackson AU, Kähönen M, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Luan J, Matoba N, Nolte IM, Padmanabhan S, Riaz M, Rueedi R, Robino A, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Vitart V, Wang Y, Ware EB, Warren HR, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Boerwinkle E, Borecki I, Broeckel U, Brown M, Brumat M, Burke GL, Canouil M, Chakravarti A, Charumathi S, Ida Chen YD, Connell JM, Correa A, de Las Fuentes L, de Mutsert R, de Silva HJ, Deng X, Ding J, Duan Q, Eaton CB, Ehret G, Eppinga RN, Evangelou E, Faul JD, Felix SB, Forouhi NG, Forrester T, Franco OH, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gigante B, Gu CC, Gu D, Hagenaars SP, Hallmans G, Harris TB, He J, Heikkinen S, Heng CK, Hirata M, Howard BV, Ikram MA; InterAct Consortium, John U, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Lin S, Liu J, Liu J, Loh M, Louie T, Mägi R, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Nalls MA, Nelson CP, Sotoodehnia N, Norris JM, O'Connell JR, Palmer ND, Perls T, Pedersen NL, Peters A, Peyser PA, Poulter N, Raffel LJ, Raitakari OT, Roll K, Rose LM, Rosendaal FR, Rotter JI, Schmidt CO, Schreiner PJ, Schupf N, Scott WR, Sever PS, Shi Y, Sidney S, Sims M, Sitlani CM, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Turner ST, Uitterlinden AG, Vollenweider P, Waldenberger M, Wang L, Wang YX, Wei WB, Williams C, Yao J, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Jonas JB, Kamatani Y, Kato N, Kooner JS, Kutalik Z, Laakso M, Laurie CC, Leander K, Lehtimäki T, Study LC, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Polasek O, Porteous DJ, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zheng W, Bouchard C, Christensen K, Evans MK, Gudnason V, Horta BL, Kardia SLR, Liu Y, Pereira AC, Psaty BM, Ridker PM, van Dam RM, Gauderman WJ, Zhu X, Mook-Kanamori DO, Fornage M, Rotimi CN, Cupples LA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Kooperberg C, Palmas W, Rice K, Morrison AC, Elliott P, Caulfield MJ, Munroe PB, Rao DC, Province MA, Levy D. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS One. 2018 Jun 18;13(6):e0198166. PMID: 29912962
  4. Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M, Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, Hoed MD, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S, Amin N, Aparicio HS, Arnett DK, Attia J, Beiser AS, Berr C, Buring JE, Bustamante M, Caso V, Cheng YC, Choi SH, Chowhan A, Cullell N, Dartigues JF, Delavaran H, Delgado P, Dörr M, Engström G, Ford I, Gurpreet WS, Hamsten A, Heitsch L, Hozawa A, Ibanez L, Ilinca A, Ingelsson M, Iwasaki M, Jackson RD, Jood K, Jousilahti P, Kaffashian S, Kalra L, Kamouchi M, Kitazono T, Kjartansson O, Kloss M, Koudstaal PJ, Krupinski J, Labovitz DL, Laurie CC, Levi CR, Li L, Lind L, Lindgren CM, Lioutas V, Liu YM, Lopez OL, Makoto H, Martinez-Majander N, Matsuda K, Minegishi N, Montaner J, Morris AP, Muiño E, Müller-Nurasyid M, Norrving B, Ogishima S, Parati EA, Peddareddygari LR, Pedersen NL, Pera J, Perola M, Pezzini A, Pileggi S, Rabionet R, Riba-Llena I, Ribasés M, Romero JR, Roquer J, Rudd AG, Sarin AP, Sarju R, Sarnowski C, Sasaki M, Satizabal CL, Satoh M, Sattar N, Sawada N, Sibolt G, Sigurdsson Á, Smith A, Sobue K, Soriano-Tárraga C, Stanne T, Stine OC, Stott DJ, Strauch K, Takai T, Tanaka H, Tanno K, Teumer A, Tomppo L, Torres-Aguila NP, Touze E, Tsugane S, Uitterlinden AG, Valdimarsson EM, van der Lee SJ, Völzke H, Wakai K, Weir D, Williams SR, Wolfe CDA, Wong Q, Xu H, Yamaji T, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium; MEGASTROKE Consortium: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nat Genet. 2018 Apr;50(4):524-537. PMID: 29531354
  5. Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Feitosa MF, Kilpeläinen TO, Richard MA, Noordam R, Aslibekyan S, Aschard H, Bartz TM, Dorajoo R, Liu Y, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Warren HR, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, Horimoto ARVR, Hsu FC, Jackson AU, Kähönen M, Kasturiratne A, Kühnel B, Leander K, Lee WJ, Lin KH, 'an Luan J, McKenzie CA, Meian H, Nelson CP, Rauramaa R, Schupf N, Scott RA, Sheu WHH, Stančáková A, d, van der Most PJ, Varga TV, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking D, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cabrera CP, Cade B, Caizheng Y, Campbell A, Canouil M, Chakravarti A; CHARGE Neurology Working Group, Chauhan G, Christensen K, Cocca M; COGENT-Kidney Consortium, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Debette S, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Fisher VA, Forouhi NG, Franco OH, Friedlander Y, Gao H; GIANT Consortium, Gigante B, Graff M, Gu CC, Gu D, Gupta P, Hagenaars SP, Harris TB, He J, Heikkinen S, Heng CK, Hirata M, Hofman A, Howard BV, Hunt S, Irvin MR, Jia Y, Joehanes R, Justice AE, Katsuya T, Kaufman J, Kerrison ND, Khor CC, Koh WP, Koistinen HA, Komulainen P, Kooperberg C, Krieger JE, Kubo M, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y; Lifelines Cohort Study, Lim SH, Lin S, Liu CT, Liu J, Liu J, Liu K, Liu Y, Loh M, Lohman KK, Long J, Louie T, Mägi R, Mahajan A, Meitinger T, Metspalu A, Milani L, Momozawa Y, Morris AP, Mosley TH Jr., Munson P, Murray AD, Nalls MA, Nasri U, Norris JM, North K, Ogunniyi A, Padmanabhan S, Palmas WR, Palmer ND, Pankow JS, Pedersen NL, Peters A, Peyser PA, Polasek O, Raitakari OT, Renström F, Rice TK, Ridker PM, Robino A, Robinson JG, Rose LM, Rudan I, Sabanayagam C, Salako BL, Sandow K, Schmidt CO, Schreiner PJ, Scott WR, Seshadri S, Sever P, Sitlani CM, Smith JA, Snieder H, Starr JM, Strauch K, Tang H, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, Waldenberger M, Wang L, Wang YX, Wei WB, Williams C, Wilson G, Wojczynski MK, Yao J, Yuan JM, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Chen YI, de Faire U, Deary IJ, Esko T, Farrall M, Forrester T, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Hung YJ, Jonas JB, Kato N, Kooner JS, Laakso M, Lehtimäki T, Liang KW, Magnusson PKE, Newman AB, Oldehinkel AJ, Pereira AC, Redline S, Rettig R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zheng W, Kamatani Y, Laurie CC, Bouchard C, Cooper RS, Evans MK, Gudnason V, Kardia SLR, Kritchevsky SB, Levy D, O'Connell JR, Psaty BM, van Dam RM, Sims M, Arnett DK, Mook-Kanamori DO, Kelly TN, Fox ER, Hayward C, Fornage M, Rotimi CN, Province MA, van Duijn CM, Tai ES, Wong TY, Loos RJF, Reiner AP, Rotter JI, Zhu X, Bierut LJ, Gauderman WJ, Caulfield MJ, Elliott P, Rice K, Munroe PB, Morrison AC, Cupples LA, Rao DC, Chasman DI. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet. 2018 Mar 1;102(3):375-400. PMID: 29455858
  6.    

2017

  1. Kobayashi T, Tsutsui H, Shimabukuro-Demoto S, Yoshida-Sugitani R, Karyu H, Furuyama-Tanaka K, Ohshima D, Kato N, Okamura T, Toyama-Sorimachi N. Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells. Int Immunol. 2017 Dec 31;29(12):551-566. PMID: 29155995
  2. Takeuchi F*, Katsuya T, Kimura R, Nabika T, Isomura M, Ohkubo T, Tabara Y, Yamamoto K, Yokota M, Liu X, Saw WY, Mamatyusupu D, Yang W, Xu S; Japanese Genome Variation Consortium, Teo YY, Kato N*. The fine-scale genetic structure and evolution of the Japanese population. PLoS One. 2017 Nov 1;12(11):e0185487. PMID: 29091727
  3. Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P, Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA, Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD; EPIC-CVD Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M, Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M, Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med. 2017 Sep 12;14(9):e1002383. PMID: 28898252
  4. Nomura A, Won HH, Khera AV, Takeuchi F, Ito K, McCarthy S, Emdin CA, Klarin D, Natarajan P, Zekavat SM, Gupta N, Peloso GM, Borecki IB, Teslovich TM, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartze DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Juang JJ, Hsiung CA, Lin SY, Wang JS, Tada H, Kawashiri MA, Inazu A, Yamagishi M, Katsuya T, Nakashima E, Nakatochi M, Yamamoto K, Yokota M, Momozawa Y, Rotter JI, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer CJ, Abecasis GR, Saleheen D, Kubo M, Kato N, Ida Chen YD, Dewey FE, Kathiresan S. Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease. Circ Res. 2017 Jun 23;121(1):81-88. PMID: 28506971
  5. Niriella MA, Pathmeswaran A, De Silva ST, Kasturiratna A, Perera R, Subasinghe CE, Kodisinghe K, Piyaratna C, Rishikesawan V, Dassanayaka AS, De Silva AP, Wickramasinghe R, Takeuchi F, Kato N, de Silva HJ. Incidence and risk factors for non-alcoholic fatty liver disease: A 7-year follow-up study among urban, adult Sri Lankans. Liver Int. 2017 May 19. doi: 10.1111/liv.13478. [Epub ahead of print] PMID: 28544258
  6. Spracklen CN, Chen P, Kim YJ, Wang X, Cai H, Li S, Long J, Wu Y, Wang YX, Takeuchi F, Wu JY, Jung KJ, Hu C, Akiyama K, Zhang Y, Moon S, Johnson TA, Li H, Dorajoo R, He M, Cannon ME, Roman TS, Salfati E, Lin KH, Guo X, Sheu WH, Absher D, Adair LS, Assimes TL, Aung T, Cai Q, Chang LC, Chen CH, Chien LH, Chuang LM, Chuang SC, Du S, Fan Q, Fann CS, Feranil AB, Friedlander Y, Gordon-Larsen P, Gu D, Gui L, Guo Z, Heng CK, Hixson J, Hou X, Hsiung CA, Hu Y, Hwang MY, Hwu CM, Isono M, Juang JJ, Khor CC, Kim YK, Koh WP, Kubo M, Lee IT, Lee SJ, Lee WJ, Liang KW, Lim B, Lim SH, Liu J, Nabika T, Pan WH, Peng H, Quertermous T, Sabanayagam C, Sandow K, Shi J, Sun L, Tan PC, Tan SP, Taylor KD, Teo YY, Toh SA, Tsunoda T, van Dam RM, Wang A, Wang F, Wang J, Wei WB, Xiang YB, Yao J, Yuan JM, Zhang R, Zhao W, Chen YI, Rich SS, Rotter JI, Wang TD, Wu T, Lin X, Han BG, Tanaka T, Cho YS, Katsuya T, Jia W, Jee SH, Chen YT, Kato N, Jonas JB, Cheng CY, Shu XO, He J, Zheng W, Wong TY, Huang W, Kim BJ, Tai ES, Mohlke KL, Sim X. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet. 2017 May 1;26(9):1770-1784. PMID: 28334899
  7. Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJ, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses; BIOS Consortium; Lifelines Cohort Study; Understanding Society Scientific group; CHD Exome+ Consortium; ExomeBP Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium, Barnes MR, Tzoulaki I, Caulfield MJ, Elliott P; UK Biobank CardioMetabolic Consortium BP working group. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet. 2017 Mar;49(3):403-415. PMID: 28135244
  8. Liu X, Lu D, Saw WY, Shaw PJ, Wangkumhang P, Ngamphiw C, Fucharoen S, Lert-Itthiporn W, Chin-Inmanu K, Chau TN, Anders K, Kasturiratne A, de Silva HJ, Katsuya T, Kimura R, Nabika T, Ohkubo T, Tabara Y, Takeuchi F, Yamamoto K, Yokota M, Mamatyusupu D, Yang W, Chung YJ, Jin L, Hoh BP, Wickremasinghe AR, Ong RH, Khor CC, Dunstan SJ, Simmons C, Tongsima S, Suriyaphol P, Kato N, Xu S, Teo YY. Characterising private and shared signatures of positive selection in 37 Asian populations. Eur J Hum Genet. 2017 Apr;25(4):499-508. PMID: 28098149
  9. Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder MJ, Brosch M, Carstensen-Kirberg M, de Craen AJ, de Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco OH, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom PE, Soininen P, Stolk L, Strauch K, Tai ES, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JB, Vineis P, Wickremasinghe AR, Wijmenga C, Yang TP, Yuan W, Zhernakova A, Batterham RL, Smith GD, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Järvelin MR, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT, Matullo G, Gieger C, Kooner JS, Grallert H, Chambers JC. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature. 2017 Jan 5;541(7635):81-86. PMID: 28002404
  10. Gregson JM, Freitag DF, Surendran P, Stitziel NO, Chowdhury R, Burgess S, Kaptoge S, Gao P, Staley JR, Willeit P, Nielsen SF, Caslake M, Trompet S, Polfus LM, Kuulasmaa K, Kontto J, Perola M, Blankenberg S, Veronesi G, Gianfagna F, Männistö S, Kimura A, Lin H, Reilly DF, Gorski M, Mijatovic V; CKDGen consortium., Munroe PB, Ehret GB; International Consortium for Blood Pressure., Thompson A, Uria-Nickelsen M, Malarstig A, Dehghan A; CHARGE inflammation working group., Vogt TF, Sasaoka T, Takeuchi F, Kato N, Yamada Y, Kee F, Müller-Nurasyid M, Ferrières J, Arveiler D, Amouyel P, Salomaa V, Boerwinkle E, Thompson SG, Ford I, Wouter Jukema J, Sattar N, Packard CJ, Shafi Majumder AA, Alam DS, Deloukas P, Schunkert H, Samani NJ, Kathiresan S; MICAD Exome consortium., Nordestgaard BG, Saleheen D, Howson JM, Di Angelantonio E, Butterworth AS, Danesh J; EPIC-CVD consortium and the CHD Exome+ consortium. Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles. Eur J Prev Cardiol. 2017 Mar;24(5):492-504. PMID: 27940953
  11.   

2016

  1. Suzuki T, Zeng Z, Zhao B, Wei Z, Tanabe M, Shimbo T, Kajio H, Kato N, Naruse M. Comparison of coronary heart disease risk among four diagnostic definitions of metabolic syndrome. J Endocrinol Invest. 2016 Nov;39(11):1337-1346. PMID: 27572249
  2. Kawamura R, Tabara Y, Tsukada A, Igase M, Ohashi J, Yamada R, Takata Y, Kawamoto R, Saito I, Onuma H, Tanigawa T, Yamada K, Kato N, Ohyagi Y, Miki T, Kohara K, Osawa H. A genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population. Physiol Genomics. 2016 Sep 23: [Epub ahead of print] PMID: 27664181
  3. Sugiyama K, Sasano T, Kurokawa J, Takahashi K, Okamura T, Kato N, Isobe M, Furukawa T. Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice. Int Heart J. 2016 May 25;57(3):341-9. PMID: 27170476
  4. Ranawaka UK, Wijekoon CN, Pathmeswaran A, Kasturiratne A, Gunasekera D, Chackrewarthy S, Kato N, Wickremasinghe AR. Risk estimates of cardiovascular diseases in a Sri Lankan community. Ceylon Med J. 2016;61:11-7. PMID: 27031973
  5. Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 May 15;25(10):2070-2081. PMID: 26911676
  6. Wen W, Kato N, Hwang JY, Guo X, Tabara Y, Li H, Dorajoo R, Yang X, Tsai FJ, Li S, Wu Y, Wu T, Kim S, Guo X, Liang J, Shungin D, Adair LS, Akiyama K, Allison M, Cai Q, Chang LC, Chen CH, Chen YT, Cho YS, Choi BY, Gao Y, Go MJ, Gu D, Han BG, He M, Hixson JE, Hu Y, Huang T, Isono M, Jung KJ, Kang D, Kim YJ, Kita Y, Lee J, Lee NR, Lee J, Wang Y, Liu JJ, Long J, Moon S, Nakamura Y, Nakatochi M, Ohnaka K, Rao D, Shi J, Sull JW, Tan A, Ueshima H, Wu C, Xiang YB, Yamamoto K, Yao J, Ye X, Yokota M, Zhang X, Zheng Y, Qi L, Rotter JI, Jee SH, Lin D, Mohlke KL, He J, Mo Z, Wu JY, Tai ES, Lin X, Miki T, Kim BJ, Takeuchi F, Zheng W, Shu XO. Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Sci Rep. 2016 Jan 20;6:17958. PMID: 26785701

2015

  1. Saw W-Y, Liu X, Khor C-C, Takeuchi F, Katsuya T, Kimura R, Nabika T, Ohkubo T, Tabara Y, Yamamoto K, Yokota M, Japanese Genome Variation consortium, Teo Y-Y, Kato N. Mapping the genetic diversity of HLA haplotypes in the Japanese populations. Sci Rep. 2015 Dec 9;5:17855. PMID: 26648100
  2. Kato N*, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Leach IM, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Mok ZY, Nakatochi M, Sapari NS, Saxena R, Stewart AF, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Bryan MS, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LL, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Liewald DC, Matsubara T, Matsushita Y, Meitinger T, Mihailov E, Milani L, Mills R, Mononen N, Müller-Nurasyid M, Nabika T, Nakashima E, Ng HK, Nikus K, Nutile T, Ohkubo T, Ohnaka K, Parish S, Paternoster L, Peng H, Peters A, Pham ST, Pinidiyapathirage MJ, Rahman M, Rakugi H, Rolandsson O, Rozario MA, Ruggiero D, Sala CF, Sarju R, Shimokawa K, Snieder H, Sparsø T, Spiering W, Starr JM, Stott DJ, Stram DO, Sugiyama T, Szymczak S, Tang WH, Tong L, Trompet S, Turjanmaa V, Ueshima H, Uitterlinden AG, Umemura S, Vaarasmaki M, van Dam RM, van Gilst WH, van Veldhuisen DJ, Viikari JS, Waldenberger M, Wang Y, Wang A, Wilson R, Wong TY, Xiang YB, Yamaguchi S, Ye X, Young RD, Young TL, Yuan JM, Zhou X, Asselbergs FW, Ciullo M, Clarke R, Deloukas P, Franke A, Franks PW, Franks S, Friedlander Y, Gross MD, Guo Z, Hansen T, Jarvelin MR, Jørgensen T, Jukema JW, Kähönen M, Kajio H, Kivimaki M, Lee JY, Lehtimäki T, Linneberg A, Miki T, Pedersen O, Samani NJ, Sørensen TI, Takayanagi R, Toniolo D; BIOS-consortium; CARDIo GRAMplusCD; LifeLines Cohort Study; InterAct Consortium, Ahsan H, Allayee H, Chen YT, Danesh J, Deary IJ, Franco OH, Franke L, Heijman BT, Holbrook JD, Isaacs A, Kim BJ, Lin X, Liu J, März W, Metspalu A, Mohlke KL, Sanghera DK, Shu XO, van Meurs JB, Vithana E, Wickremasinghe AR, Wijmenga C, Wolffenbuttel BH, Yokota M, Zheng W, Zhu D, Vineis P, Kyrtopoulos SA, Kleinjans JC, McCarthy MI, Soong R, Gieger C, Scott J, Teo YY, He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat Genet. 2015 Nov;47(11):1282-93. PMID: 26390057
  3. Deng L, Hoh B-P, Lu D, Saw W-Y, Ong R T-H, Kasturiratne A, de Silva HJ, Zilfalil BA, Kato N, Wickremasinghe AR, TeoY-Y, Xu S. Dissecting the genetic structure and admixture of four geographical Malay populations. Sci Rep. 2015 Sep 23;5:14375. PMID: 26395220
  4. Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V, Wahl S, Elliott HR, Rota F, Scott WR, Zhang W, Tan ST, Campanella G, Chadeau-Hyam M, Yengo L, Richmond RC, Adamowicz-Brice M, Afzal U, Bozaoglu K, Mok ZY, Ng HK, Pattou F, Prokisch H, Rozario MA, Tarantini L, Abbott J, Ala-Korpela M, Albetti B, Ammerpohl O, Bertazzi PA, Blancher C, Caiazzo R, Danesh J, Gaunt TR, de Lusignan S, Gieger C, Illig T, Jha S, Jones S, Jowett J, Kangas AJ, Kasturiratne A, Kato N, Kotea N, Kowlessur S, Pitkäniemi J, Punjabi P, Saleheen D, Schafmayer C, Soininen P, Tai ES, Thorand B, Tuomilehto J, Wickremasinghe AR, Kyrtopoulos SA, Aitman TJ, Herder C, Hampe J, Cauchi S, Relton CL, Froguel P, Soong R, Vineis P, Jarvelin MR, Scott J, Grallert H, Bollati V, Elliott P, McCarthy MI, Kooner JS. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endocrinol. 2015 Jul;3(7):526-34. PMID: 26095709
  5. Akiyama K, Liang YQ, Isono M, Kato N*. Investigation of Functional Genes at Homologous Loci Identified Based on Genome-wide Association Studies of Blood Lipids via High-fat Diet Intervention in Rats using an in vivo Approach. J Atheroscler Thromb. 2015 May 20;22(5):455-80. PMID: 25445557
  6. Takeuchi F, Isono M, Yamamoto K, Yokota M, Akiyama K, Katsuya T, Kim H-S, Park JE, Jang Y, Lee Ji-Y, AGEN Consortium, Lee J-Y, Kato N*. Heterogeneous effects of association between blood pressure loci and coronary artery disease in east Asian individuals.Circ J. 2015 Mar 25;79(4):830-8. PMID: 25740055
  7. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 2015 Mar 15;24(6):1791-800. PMID: 25429064
  8. Kasturiratne A, Akiyama K, Niriella MA, Takeuchi F, Isono M, Dassanayake AS, De Silva AP, Wickremasinghe RA, Kato N, de Silva HJ. Association of genetic variants with non-alcoholic fatty liver disease in an urban Sri Lankan community Liver Int. 2015 Feb;35(2):676-9. PMID: 24947803
  9. Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Hee Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Tomohiro K, Oh J, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung K, Nabika T, Bae JB, Lee M, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ. Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. Diabetes. 2015 Jan;64(1):291-8. PMID: 25187374

2014

  1. Akiyama K, Takeuchi F, Isono M, Chakrawarthy S, Nguyen QN, Wen W, Yamamoto K, Katsuya T, Kasturiratne A, Pham ST, Zheng W, Matsushita Y, Kishimoto M, Do LD, Shu XO, Wickremasinghe AR, Kajio H, Kato N*. Systematic Fine-Mapping of Association with BMI and Type 2 Diabetes at the FTO Locus by Integrating Results from Multiple Ethnic Groups. PLoS One. 2014 Jun 30;9(6):e101329. PMID: 24978468
  2. Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, Shimizu Y, Hosaka T, Goto M, Kato N, Okamura T, Suematsu M, Yokoyama S, Toyama-Sorimachi N. The Histidine Transporter SLC15A4 Coordinates mTOR-Dependent Inflammatory Responses and Pathogenic Antibody Production. Immunity. 2014 Sep 18;41(3):375-88. PMID: 25238095
  3. Kim YK, Kim Y, Hwang MY, Shimokawa K, Won S, Kato N, Tabara Y, Yokota M, Han BG, Lee JH, Kim BJ. Identification of a genetic variant at 2q12.1 associated with blood pressure in East-Asians by genome-wide scan including gene-environment interactions.BMC Med Genet. 2014 Jun 5;15(1):65. PMID: 24903457
  4. Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T. Meta-analysis of genome-wide Hum Mol Genet. 2014 Oct 15;23(20):5492-504 PMID: 24861553
  5. Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi MO, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Huey-Herng Sheu W, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T; Hematology CHARGE Group Working, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES. Multiple Non-glycemic Genomic Loci Are Newly Associated with Blood Level of Glycated Hemoglobin in East Asians. Diabetes. 2014 Jul;63(7):2551-62. PMID: 24647736
  6. Xi B, Takeuchi F, Meirhaeghe A, Kato N, Chambers JC, Morris AP, Cho YS, Zhang W, Mohlke KL, Kooner JS, Shu XO, Pan H, Tai ES, Pan H, Wu JY, Zhou D, Chandak GR; DIAGRAM Consortium; AGEN-T2D consortium; SAT2D Consortium. Associations of genetic variants in/near BMI-associated genes with type 2 diabetes: A systematic meta-analysis. Clin Endocrinol (Oxf). 2014 Nov;81(5):702-10. PMID: 24528214
  7. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium & Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44. PMID: 24509480
  8. Aoyama-Mani C, Kawachi S, Ogawa Y, Kato N*. Vascular complications and coagulation-related changes in the perioperative period in Japanese patients undergoing non-cardiac surgery. J Atheroscler Thromb. 2014;21(5):414-34. PMID: 24351790
  9. Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet. 2014 Feb 15;23(4):1108-19. PMID: 24105470

2013

  1. Kato N*. Candidate genes revisited in the genetics of hypertension and blood pressure. Hypertens Res. 2013 Dec;36(12):1032-4. PMID: 23945960
  2. Kelly TN, Takeuchi F, Tabara Y, Edwards TL, Kim YJ, Chen P, Li H, Wu Y, Yang CF, Zhang Y, Gu D, Katsuya T, Ohkubo T, Gao YT, Go MJ, Teo YY, Lu L, Lee NR, Chang LC, Peng H, Zhao Q, Nakashima E, Kita Y, Shu XO, Kim NH, Tai ES, Wang Y, Adair LS, Chen CH, Zhang S, Li C, Nabika T, Umemura S, Cai Q, Cho YS, Wong TY, Zhu J, Wu JY, Gao X, Hixson JE, Cai H, Lee J, Cheng CY, Rao DC, Xiang YB, Cho MC, Han BG, Wang A, Tsai FJ, Mohlke K, Lin X, Ikram MK, Lee JY, Zheng W, Tetsuro M, Kato N, He J. Genome-Wide Association Study Meta-Analysis Reveals Transethnic Replication of Mean Arterial and Pulse Pressure Loci. Hypertension. 2013 Nov;62(5):853-9. PMID: 24001895
  3. Kato N*. Insights into the genetic basis of type 2 diabetes. J Diabetes Invest. 2013 May;4(3):233-44.
  4. Wang X, Chua HX, Chen P, Ong RT, Sim X, Zhang W, Takeuchi F, Liu X, Khor CC, Tay WT, Cheng CY, Suo C, Liu J, Aung T, Chia KS, Kooner JS, Chambers JC, Wong TY, Tai ES, Kato N, Teo YY. Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies. Hum Mol Genet. 2013 Jun 1;22(11):2303-11. PMID: 23406875
  5. Takeuchi F, Yamamoto K, Isono M, Katsuya T, Akiyama K, Ohnaka K, Rakugi H, Yamori Y, Ogihara T, Takayanagi R, Kato N*. Genetic impacts on uric acid concentration and hyperuricemia in the Japanese population. J Atheroscler Thromb. 2013;20(4):351-67. PMID: 23238572
  6. Chackrewarthy S, Gunasekera D, Pathmeswaren A, Wijekoon CN, Ranawaka UK, Kato N, Takeuchi F, Wickremasinghe AR. A Comparison between Revised NCEP ATP III and IDF Definitions in Diagnosing Metabolic Syndrome in an Urban Sri Lankan Population: The Ragama Health Study. ISRN Endocrinol. 2013;2013:320176. PMID: 23533799
  7. Pinidiyapathirage MJ, Kasturiratne A, Ranawaka UK, Gunasekara D, Wijekoon N, Medagoda K, Perera S, Takeuchi F, Kato N, Warnakulasuriya T, Wickremasinghe AR.The burden of diabetes mellitus and impaired fasting glucose in an urban population of Sri Lanka. Diabetic Med. 2013 Mar;30(3):326-32. PMID: 22998091
  8. Kasturiratne A, Weerasinghe S, Dassanayake AS, Rajindrajith S, de Silva AP, Kato N, Wickremasinghe AR, de Silva HJ. Influence of non-alcoholic fatty liver disease on the development of diabetes mellitus. J Gastroenterol Hepatol. 2013 Jan;28(1):142-7. PMID: 22989165

2012

  1. Okamura T, Yanobu-Takanashi R, Takeuchi F, Isono M, Akiyama K, Shimizu Y, Goto M, Liang Y-Q, Yamamoto K, Katsuya T, Fujioka A, Ohnaka K, Takayanagi R, Ogihara T, Yamori Y, Kato N*. Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes. PLoS One. 2012;7(11):e49055. PMID: 23173044
  2. Takeuchi F, Isono M, Katsuya T, Yokota M, Yamamoto K, Nabika T, Shimokawa K, Nakashima E, Sugiyama T, Rakugi H, Yamaguchi S, Ogihara T, Yamori Y, Kato N*. Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. PLoS One. 2012;7(9):e46385. PMID: 23050023
  3. Muhihi A, Njelekela M, Mpembeni R, Masesa Z, Kitamori K, Mori M, Kato N, Mtabaji J, Yamori Y. Physical activity and cardiovascular disease risk factors among young and middle-aged men in urban Mwanza, Tanzania. Pan Afr Med J. 2012;11:11. PMID: 22368754
  4. Xi B, Takeuchi F, Chandak GR, Kato N, Pan HW; AGEN-T2D Consortium, Zhou DH, Pan HY, Mi J. Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals. Diabetologia. 2012 Oct;55(10):2660-6. PMID: 22869321
  5. Takeuchi F, Yamamoto K, Katsuya T, Sugiyama T, Nabika T, Ohnaka K, Yamaguchi S, Takayanagi R, Ogihara T, Kato N*. Reevaluation of blood pressure and hypertension association with seven candidate genes by replication study and meta-analysis with larger sample size. Hypertens Res. 2012 Aug;35(8):825-31. PMID: 22456346
  6. Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; The KidneyGen Consortium; The CKDGen Consortium, Albrecht E; The GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature Genet. 2012 Jul 15;44(8):904-909. PMID: 22797727
  7. Kato N*. Ethnic diversity in type 2 diabetes genetics between East Asians and Europeans. J Diabetes Invest. 2012 Aug;3(4):349-351.
  8. Kato N*. Ethnic differences in genetic predisposition to hypertension. Hypertens Res. 2012 Jun;35(6):574-81. PMID: 22476227
  9. Li H, Kilpelainen T, Liu C, Zhu J, Liu Y, Hu C, Yang Z, Bao W, Cha S, Wu Y, Yang T-L, Sekine A, Choi BY, Yajnik CS, Zhou D, Takeuchi F, Yamamoto K, Chan JC, Mani KR, Been LF, Imamura M, Nakashima E, Lee N, Fujisawa T, Karasawa S, Wen W, Lu W, Chang Y-C, Xiang Y-B, Gao Y, Liu S, Song Y, Kwak SH, Shin HD, Park KS, Fall C, Kim JY, Sham PC, Lam KSL, Zheng W, Shu XO, Deng H-W, Ikegami H, Sanghera DK, Chuang L-M, Liegang Liu, Hu R, Kim Y-M, Daimon M, Hotta K, Jia W, Kooner JS, Chambers JC, Chandak GR, Ma RC, Maeda S, Dorajoo R, Yokota M, Takayanagi R, Kato N, Lin X, Loos RJF. Association of genetic variation in FTO with risk of obesity and type 2 diabetes in up to 96,551 East and South Asians. Diabetologia. 2012 Apr;55(4):981-95. PMID: 22109280
  10. Okada Y, Kubo M, Ohmiya H, Takahashi A, Kumasaka N, Hosono N, Maeda S, Wen W, Dorajoo R, Go MJ, Zheng W, Kato N, Wu J-Y, Lu Q, GIANT consortium, Tsunoda T, Yamamoto K, Nakamura Y, Kamatani N, Tanaka T. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nature Genet. 2012 Feb 19;44(3):302-6. PMID: 22344221
  11. Wen W, Cho Y-S, Zheng W, Dorajoo R, Kato N, Lu Q, Chen C-H, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao Y-T, Saw S-M, Go M-J, Takeuchi F, Chang L-C, Kokubo Y, Liang J, Hao M, Marchand LL, Zhang Y, Hu Y, Wong T-Y, Long J, Han B-G, Kubo M, Yamamoto K, Su M-H, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP-K, Cai Q, Tsunoda T, Tsai F-J, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang Y-B, Maeda S, Ong RTH, Li C, Nakamura Y, Aung T, Kamatani N, Liu J-J, Lu W, Yokota M, Seielstad M, Fann CSJ, The Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu J-Y, Lee J-Y, Hu FB, Tanaka T, Tai ES, Shu X-O. Meta-analysis identifies common variants associated with body mass index in east Asians. Nature Genet. 2012 Feb 19;44(3):307-311. PMID: 22344219

2011

  1. Cho YS, Chen C-H, Hu C, Long J, Ong RTH, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang Y-C, Kwak SH, Ma RCW, Yamamoto K, Adair LS, Aung T, Cai Q, Chang L-C, Chen Y-T, Gao Y, Hu FB, Kim H-L, Kim S, Kim YJ, Lee JJ-M, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, NgDP-K, Tay WT, Tsai F-J, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang T-J, Bao Y, Hedman AK, P Morris AP, McCarthy MI, DIAGRAM consortium36, MuTHER consortium36, Takayanagi R, Park KS, Jia W, Chuang L-M, ChanJCN, Maeda S, Kadowaki T, Lee J-Y, Wu J-Y, TeoYY, Tai ES, Shu XO, Mohlke KL, Kato N, Han B-G, Seielstad M. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet. Dec 11;44(1):67-72. PMID: 22158537
  2. Kato N*, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS, He J. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet. 2011, Jun;43(6):531-8. PMID: 21572416
  3. Kooner JS*, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, Been LF, Chia K-S, Dimas AS, Hassanali N, Jafar T, Jowett JBM, Venkatesan R, Rees SD, Takeuchi F, Young R, Aung T, Basit A, Chidambaram M, Das D, Grunberg E, Hedman AK, Hydrie ZI, Islam M, Khor C-C, Kowlessur S, Kristensen MM, Liju S, Lim W-Y, Matthews DR, Liu J, Morris AP, Nica AC, Pinidiyapathirage JM, Prokopenko I, Rasheed A, Samuel M, Shah N, Shera AS, Small KS, Suo C, Wickremasinghe AR, Wong TY, Yang M, Zhang F, DIAGRAM, MuTHER, Abecasis GR, Barnett AH, Caulfield M, Deloukas P, Frayling T, Froguel P, Kato N, Katulanda P, Kelly MA, Liang J, Mohan V, Sanghera DK, Scott J, Seielstad M, Zimmet PZ, Elliott P, Teo YY, McCarthy MI, Danesh J, Tai ES, Chambers JC*. Genome-wide association study in people of South Asian ancestry identifies six novel susceptibility loci for Type 2 Diabetes. Nat Genet. Aug 28;43(10):984-9. PMID: 21874001
  4. Takeuchi F*, Kobayashi S, Ogihara T, Fujioka A, Kato N. Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. Genome Res. 2011, Jul;21(7):1122-30. PMID: 21441355
  5. Njelekela M, Muhihi A*, Mpembeni R, Masesa Z, Kitamori K, Mori-Yamori M, Kato N, Mtabaji J, Yamori Y. Prevalence of Cardiovascular Disease Risk Factors among Young and Middle-age Men in Urban Mwanza, Tanzania. J Public Health. 2011, 19(6):553-61.
  6. Takeuchi F, Yamamoto K, Katsuya T, Nabika T, Sugiyama T, Fujioka A, Isono M, Ohnaka K, Fujisawa T, Nakashima E, Ikegami H, Nakamura J, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Takayanagi R, Kato N*. Association of obesity susceptibility genetic variants with type 2 diabetes in the Japanese. Diabetologia. 2011, 54(6):1350-9. PMID: 21369819
  7. Dassanayake AS, Kasturiratne A, Niriella MA, Kalubovila U, Rajindrajith S, De Silva AP, Kato N, Wickremasinghe R and de Silva J*. Prevalence of acanthosis nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome. BMC Research Notes. 2011, 4(1):25. PMID: 21276250
  8. Sasawatari S, Okamura T, Kasumi E, Tanaka-Furuyama K, Yanobu-Takanashi R, Shirasawa S, Kato N, Toyama-Sorimachi N*. The solute carrier family 15A4 regulates TLR9 and NOD1 functions in the innate immune system and promotes colitis in mice. Gastroenterology. Jan 26. 2011, 140(5):1513-25. PMID: 21277849
  9. Takeuchi F, Isono M, Nabika T, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Ogihara T, Yamori Y, Fujioka A, Kato N*. Confirmation of ALDH2 as a major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in Japanese. Circ J. 2011, 75(4):911-8. PMID: 21372407

2010

  1. Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S. Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS One. 2010 Dec 9;5(12):e15553. PMID: 21151568
  2. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N*. Blood pressure and hypertension are associated with seven loci showing male-specific interaction with age among the Japanese. Circulation. 2010, 121(21):2302-9. PMID: 20479155
  3. Takeuchi F, Kashida M, Okazaki O, Tanaka Y, Fukuda S, Kashima T, Hosaka S, Hiroe M, Kimura S, Kato N*. Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients. Circ J. 2010, 74:977-82. PMID: 20339191
  4. Taniguchi-Yanai K, Koike Y, Hasegawa T, Furuta Y, Serizawa M, Ohshima N, Kato N*, Yanai K*. Identification and characterization of glucocorticoid receptor-binding sites in the human genome. J Recept Signal Transduct Res. 2010, 30(2):88-105. PMID: 20163328
  5. Takeuchi F, Katsuya T, Charkrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N*. Common variants at the GCK, GCKR, G6PC2-ABCB11,and MTNR1B lociare associatedwith fasting glucose in two Asian populations. Diabetologia. 2010, 53(2):299-308. PMID: 19937311

2009

  1. Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N*. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes. 2009, 58(7):1690-9. PMID: 19401414
  2. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Makino Y, Wakahara S, Inoki I, Miyamori I, Pinet F; the Genomic Disease Outcome Consortium (G-DOC) Study Investigators. Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blocker. Diabetes Care. 2009, 32(8):1485-90. PMID: 19509012
  3. Takeuchi F, Nabika T, Isono M, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Yamori Y, Ogihara T, Kato N*. Evaluation of genetic loci influencing adult height in the Japanese population. J Hum Genet. 2009, 54(12):749-52. PMID: 19834501
  4. Tsuchihashi-Makaya M, Serizawa M, Yanai K, Katsuya T, Takeuchi F, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environmental interaction regarding alcohol metabolizing enzymes in the Japanese general population. Hypertens Res. 2009, 32(3):207-13. PMID: 19262484
  5. Fujimoto T, Miyasaka K, Koyanagi M, Tsunoda T, Baba I, Doi K, Ohta M, Kato N, Sasazuki T, Shirasawa S. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS ONE. 2009, 4:e4240. Epub 2009 Jan 21. PMID: 19156225
  6. Tsuchihashi-Makaya M, Hamaguchi S, Kinugawa S, Yokota T, Goto D, Yokoshiki H, Kato N, Takeshita A, Tsutsui H; JCARE-CARD Investigators. Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J. 2009, 73(10):1893-900. PMID: 19644216
  7. Dassanayake AS, Kasthuriratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, Makaya M, Mizoue T, Kato N, Wickremasinghe AR, de Silva HJ. Prevalence and risk factors for non-alcoholic fatty liver disease (NAFLD) among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009, 24(7):1284-8. PMID: 19476560
  8. Morii T, Ohno Y, Kato N, Hirose H, Kawabe H, Hirao K, Eguchi T, Maruyama T, Hayashi M, Saito I, Yazaki Y, Saruta T. CD36 SNP is associated with variation in LDL-cholesterol in young Japanese men. Biomarkers. 2009, 14(4):207-12. PMID: 19489681
  9. Tsuchihashi-Makaya M, Kato N, Chishaki A, Takeshita A, Tsutsui H. Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure. Circ J. 2009, 73(2):280-7. PMID: 19096191
  10. Tsukahara T, Nakashima E, Watarai A, Hamada Y, Naruse K, Kamiya H, Nakamura N, Kato N, Hamajima N, Sekido Y, Niwa T, Tomita M, Oiso Y, Nakamura J. Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients. Diabetes Res Clin Pract. 2009, 84(2):179-86. PMID: 19269054
  11. Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H. Fas Promoter Region Gene Polymorphism Is Associated With An Increased Risk For Myocardial Infarction. Hypertens Res. 2009, 32(4):261-4. PMID: 19262492
  12. Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 2009 Mar;5(3):e1000433. Epub 2009 Mar 20. PMID: 19300499

2008

  1. Kato N*, Miyata T, Tabara Y, Katsuya T, Yanai K, Hanada H, Kamide K, Nakura J, Kohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakayama T, Soma M, Hata A, Fujioka A, Kawano Y, Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara T, Sugano S, Miki T, Tomoike H. High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet. 2008, 17:617-27. PMID: 18003638
  2. Ochiai Y, Liang YQ, Serizawa M, Kato N*. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. Physiol Genomics. 2008, 35:330-40. PMID: 18796534
  3. Takeuchi F, Ochiai Y, Serizawa M, Yanai K, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q. J Hum Genet. 2008, 53:314-24. PMID: 18259684
  4. Takeuchi F, Serizawa M, Kato N*. HapMap coverage for SNPs in the Japanese population. J Hum Genet. 2008, 53:96-9. PMID: 18043864
  5. Serizawa M, Nabika T, Ochiai Y, Takahashi K, Yamaguchi S, Makaya M, Kobayashi S, Kato N*. Association between PRKCH gene polymorphisms and subcortical silent brain infarction. Atherosclerosis. 2008, 199:340-5. PMID: 18164711
  6. Kato N*, Liang YQ, Ochiai Y, Birukawa N, Serizawa M, Jesmin S. Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. Hypertens Res. 2008, 31:1963-75. PMID: 19015604
  7. Kato N*, Liang YQ, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. Eur J Pharmacol. 2008, 584:376-89. PMID: 18295756
  8. Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics. 2008, 91:451-7. PMID: 18329245

2007

  1. Takeuchi F, Yanai K, Inomata H, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search of type 2 diabetes susceptibility gene on chromosome 20q. Biochem Biophys Res Commun. 2007, 357:1100-6. PMID: 17466274
  2. Jesmin S, Maeda S, Mowa CN, Zaedi S, Togashi H, Prodhan SH, Yamaguchi T, Yoshioka M, Sakuma I, Miyauchi T, Kato N. Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat. Eur J Pharmacol. 2007, 574:158-71. PMID: 17689527
  3. Fujimoto T, Koyanagi M, Baba I, Nakabayashi K, Kato N, Sasazuki T, Shirasawa S. Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J Hum Genet. 2007, 52:978-84. PMID: 17934691
  4. Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology. 2007, 148:2453-7. PMID: 17303661

2006

  1. Konoshita T, Wakahara S, Mizuno S, Motomura M, Aoyama C, Makino Y, Kawai Y, Kato N, Koni I, Miyamori I, Mabuchi H. Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. Diabetes Care. 2006, 29:848-52. PMID: 16567826
  2. Manabe N, Hoshino A, Liang YQ, Goto T, Kato N, Yamamoto K. Quantum dot as a drug tracer in vivo. IEEE Trans Nanobioscience. 2006, 5:263-7. PMID: 17181025
  3. Takeuchi F, Yamamoto K. Effectiveness of realistic vaccination strategies for contact networks of various degree distributions. J Theor Biol. 2006, 243(1):39-47. PMID: 16860340

2005

  1. Takeuchi F, Yanai K, Morii T, Ishinaga Y, Taniguchi-Yanai K, Nagano S, Kato N. Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. Genetics. 2005, 170:291-304. PMID: 15716494
  2. Watanabe T, Iizuka Y, Liang Y-Q, Inomata H, Gotoda T, Yanai K, Isobe M, Kato N*. Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony Biochem Biophys Res Commun. 2005, 329: 879-87. PMID: 15752738
  3. Inomata H, Watanabe T, Iizuka Y, Liang Y-Q, Mashimo T, Nabika T, Ikeda K, Yanai K, Gotoda T, Yamori Y, Isobe M, Kato N*. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Hypertens Res. 2005, 28: 273-81. PMID: 16097372

II. Presentations at International Scientific Meetings

  1. Niriella MA, Kasturiratna KATT, De Silva ST, Ranasinghe A, Perera KR, Subasinghe SKCE, Kodisinghe SK, Piyaratna TACL, Vithiya K, Dassanayaka AS, De Silva AP, Pathmeswaran A, Wickramasinghe AR, Kato N, de Silva HJ. Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans: a prospective 7-year follow-up study. American Association for the Study of Liver Diseases, The liver meeting, San Francisco, USA, November 2018.
  2. Kato N. Role of epigenome in hypertension. 27th Scientific Meeting of the International Society of Hypertension. Beijing, China, September 2018.
  3. Kato N. Genetics/genomics of hypertension with consideration of ethnic differences. Cardiovascular Genetics, Satellite Symposium of ISH 2018. Shanghai, China, September 2018.
  4. Imai-Okazaki A, Takeuchi F, Arakawa R, Miyo K, Saito K, Ott J, Kato N. Incorporation of originally-developed statistical genetics methods into a clinical sequencing platform to improve the efficiency and quality of variant annotation. Keystone Symposia. One million genomes: from discovery to health, Hanover, Germany, June 2018.
  5. Niriella MA, De Silva ST, Kasturiratna A, Perera KR, Subasinghe SKCE, Kodisinghe SK, Piyaratna TACL, Vithiya K, Dassanayaka AS, De Silva AP, Pathmeswaran A, Wickramasinghe AR, Takeuchi F, Kato N, de Silva HJ. Lean-NAFLD is the strongest predictor of future obesity among urban adult Sri Lankans: results from a prospective, community cohort follow-up study. UEG week 2017, Barcelona, Spain, October 2017.
  6. Kato N. Medical Genomics Japan Database: Introduction of Global picture and somatic cancer group. ICBI Seminar Series. Washington DC, USA, February, 2017.
  7. Spracklen CN, Kim Y.J, Chen P, Sim X, Cai H, Li S, Long J, Wu Y, Wang X, Wang YX, Takeuchi F, Jung KJ, Wu JY, Johnson T.A, Li H, Dorajoo R, He M, Akiyama K, Zhang Y, Hou X, Hu C, Moon S, Salfati E, AGEN Consortium. Association analyses of up to 72,043 East Asian individuals and trans-ancestry analyses with up to 186,265 European individuals reveal new loci associated with cholesterol and triglyceride levels. 61st annual meeting of the American Society of Human Genetics, Vancouver, Canada, October, 2016.
  8. Niriella MA, De Silva ST, Kasturiratna A, Perera KR, Subasinghe SKCE, Kodisinghe SK, Piyaratna TACL, Vithiya K, Dassanayaka AS, De Silva AP, Pathmeswaran A, Wickramasinghe AR, Kato N, de Silva HJ. Lean non-alcoholic fatty liver disease (Lean-NAFLD): characteristics and risk factors from a community cohort follow up study. UEG week 2016, Vienna, Austria, October 2016.
  9. Kato N. DNA methylation and hypertension. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  10. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q, Kato N. Epigenetic changes in the brain with high-salt intervention in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  11. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q, Kato N. Epigenetic changes in the liver with high-fat-diet intervention in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  12. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q, Kato N. Epigenetic changes in the liver with dexamethasone administration in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  13. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q, Kato N. Comparison of epigenetic changes in the liver between Tg-CETP rat and SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  14. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q, Kato N. Comparison of epigenetic changes in the liver between RNO4-derived congenic rat and progenitor strains. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  15. Konoshita T, Sakai A, Kaeriyama S, Urabe M, Nakaya T, Yamada M, Ichikawa M, Sato S, Yamamoto K, Imagawa M, Fujii M, Zenimaru Y, Suzuki J, Makino Y, Ishizuka T, Kato N. Association study of angiotensinase A (ENPEP) genotype with diabetic nephropathy. 26th European Meeting on Hypertension and Cardiovascular Protection. Paris, France, June, 2016.
  16. Kato N. Genomic medicine in NCDs: findings from Asians/ South Asians to global collaboration. 25th Anniversary International Scientific Conference University of Kelaniya. Ragama, Sri Lanka, April 2016.
  17. Niriella M, Kasturiratna A, De Silva S, Perera R, Subasinghe C, Kodisinghe K, Piyarathna C, Rishikeshavan V, Dassanayake A, De Silva A, Pathmeswaran A, Kato N, de Silva J. Incidence and risk factors for non-alcoholic fatty liver disease in an urban, adult Sri Lankan population  Ea community cohort follow-up study. UEG week 2015, Barcelona, Spain, October 2015.
  18. Takeuchi F, Katsuya T, Kimura R, Nabika T, Okubo T, Tabara Y, Yamamoto K, Yokota M, Saw W-Y, Teo YY, Kato N. The fine-scale genetic structure of the Japanese population: estimation of genetic materials derived from Asians and the basis of genetic differentiation. 60th annual meeting of the American Society of Human Genetics, Baltimore, USA, October, 2015.
  19. Kawamura R, Tabara Y, Igase M, Takata Y, Kawamoto R, Saito I, Onuma H, Kohara K, Tanigawa T, Yamada K, Kato N, Miki M, Osawa H. Rs10401670 was identified as a possible functional quantitative trait locus for circulating resistin by a genome-wide association study in Japanese. 75th Scientific Session of American Diabetic Association. Boston, USA, June 2015.
  20. Loh M, et al. on behalf of iGEN-BP. Trans-ethnic genome-wide association study identifies 15 new genetic loci influencing blood pressure traits, and implicates a role for DNA methylation: the International Genetics of Blood Pressure (iGEN-BP) Study. 59th annual meeting of the American Society of Human Genetics, San Diego, USA, October, 2014.
  21. Kato N. Towards elucidation of pathological basis of intractable tumors. International Symposium on Pheochromocytoma and Paraganglioma 2014. Kyoto, Japan, September 2014.
  22. Kato N. Genetics of NAFLD/ NASH. 127th Anniversary International Medical Congress of Sri Lanka Medical Association. Colombo, Sri Lanka, July 2014.
  23. Kato N. Can rat genetics help to improve human genetics? Cardiovascular Genetics Satellite 2014. Rome, Italy, June 2014.
  24. Kawamura R, Tabara Y, Igase M, Takata Y, Kawamoto R, Saito I, Tanigawa T, Onuma H, Kohara K, Kato N, Miki M, Osawa H. Resistin SNP-358, SNP-420, and rs1423096 were identified as major quantitative trait loci for serum resistin by a genome-wide association study in Japanese. 74th Scientific Session of American Diabetic Association. San Francisco, USA, June 2014.
  25. Konoshita T, Yamada M, Ichikawa M, Sato S, Imagawa M, Makino Y, Fujii M, Wakahara S, Zenimaru Y, Arakawa K, Suzuki J, Kato N. Measurement of soluble angiotensin-IV receptor (s-AT4), identified through systemic transcriptome analysis of hypertensive and diabetic renal tissue. 23rd European Meeting on Hypertension and Cardiovascular Protection. Milan, Italy, June, 2013.
  26. Kato N. Global genomics of BP. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  27. Akiyama K, Liang Y-Q, Kato N. Evaluation of human lipid-associated genes and methylation in SHR fed on high lipid diet. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  28. Akiyama K, Liang Y-Q, Kato N. Identification of "neutralizing" gene-gene interaction in the regulation of blood pressure in the SHR-related strains. Exploration of genetic loci controlling serum cholesterol concentration in the SHR-related strains: identification of two novel cholesterol loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  29. Liang Y-Q, Akiyama K, Kato N. Exploration of genetic loci controlling serum cholesterol concentration in the SHR-related strains: identification of two novel cholesterol loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  30. Liang Y-Q, Akiyama K, Kato N. Exploration of cardiac hypertrophy loci in the SHR-related strains: confirmation of the endonuclease G locus and identification of novel loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  31. Konoshita T, Kimura T, Fujii M, Makino Y, Wakahara S, Inaba S, Miyamori I, Kato N. A systematic review of pharmacogenetics in the renin angiotensin system  Ethe genetic variants and inter-individual variation in blood pressure response to the blocking agents. 22nd European Meeting on Hypertension and Cardiovascular Protection. London, UK, April, 2012.
  32. Matsushita Y, Kishimoto M, Takahashi Y, Kanagawa S, Noda M, Thai SP, Ngoc QN, Hong HPT, Doan LD, Lan VN, Zeng Z-P, Wickremasinghe AR, Naruse M, Kato N, Kajio H. The Cutoff Levels of Waist Circumference for Predicting the Presence of the Clustering of Metabolic Risk Factors in some Asian Populations. IDF World Diabetes Congress 2011, Dubai, UAE, December, 2011.
  33. Horikoshi M, Wiltshire S, Kato N, Asimit J, Rayner N, Robertson N, Takeuchi F, Mahajan A, Teo Y-Y, Zeggini E, Morris A, McCarthy M, T2D-GENES. Trans-ethnic fine-mapping of Type 2 Diabetes susceptibility loci using a “Cosmopolitan Ereference panel for imputation. 61st annual meeting of the American Society of Human Genetics and the International Congress of Human Genetics 2011, Montreal, Canada, Oct 14, 2011.
  34. Kato N. GWAS of hypertension-associated disease in the Japanese. 20th KOGO Conference. Osong, Korea, September, 2011.
  35. Horikoshi M, Kato N, Wiltshire S, Asimit J, Rayner NW, Robertson N, Takeuchi F, Teo YY, Zeggini, E, McCarthy M, Morris A, T2D-GENES Consortium. Trans-Ethnic Fine-Mapping of T2D Susceptibility Loci. ADA Annual Meeting 2011, San Diego, USA, June, 2011.
  36. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. 5th Oriental Congress of Cardiology, Shanghai, China, May, 2011.
  37. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. The National University of Singapore, Advanced genomics symposium, Singapore, February, 2011.
  38. Takeuchi F, Kato N. Testing heterogeneity of quantitative trait variance among genotype classes guides fine mapping of association signals. 60th annual meeting of the American Society of Human Genetics, Washington DC, USA, November, 2010.
  39. Kato N. Genetic susceptibility to diabetes and associated diseases in the Japanese. 8th IDF WPR Congress. Busan, Korea, October, 2010.
  40. Kato N. Genome-wide exploration of genetic susceptibility to cardiometabolic diseases. International Congress of Pathophysiology & International SHR Symposium 2010. Montreal, Canada, September, 2010.
  41. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N. Blood pressure and hypertension are associated with seven loci in the Japanese population. 23rd Scientific Meeting International Society of Hypertension. Vancouver, Canada, September, 2010.
  42. Kato N. Genetic susceptibility to cardiovascular disease and its risk factors in the Japanese. 19th KOGO Conference. Seoul, Korea, September, 2010.
  43. Kato N. Risk of myocardial infarction and stroke among Asians. 10th South East Asia Regional Scientific Meeting of the International Epidemiological Association, Colombo, Sri Lanka, May, 2010.
  44. Takeuchi F, Katsuya T, Yamamoto K, Nabika T, Ranawaka U, Sugiyama T, Fujioka A, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Chakrewarthy S, Wickremasinghe R, and Kato N, for the NIBIO GWA Study and Ragama Health Study. Confirmation of eight loci associated with measures of obesity in two Asian populations with substantial ethnic heterogeneity. 27th annual scientific meeting of the Obesity Society, Washington DC, USA, October, 2009.
  45. Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N for the NIBIO GWA Study. Ethnic diversity in fine mapping of the susceptibility loci G6PC2-ABCB11 for fasting glucose and CDKAL1 for type 2 diabetes. 59th annual meeting of the American Society of Human Genetics, Honolulu, USA, October, 2009.
  46. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Kimura T, Fujii M, Makino Y, Wakahara S, Arakawa K, Inoki I, Miyamori I, Pinet P. Genetic Variant of the Renin Angiotensin System Influences Blood Pressure Response to Angiotensin Receptor Blocker. 19th European Meeting on Hypertension, Milan, Italy, June, 2009.
  47. Kato N, Liang Y-Q, Ochiai Y, Serizawa M. Dissection of phenotypic traits associated with metabolic syndrome and positional cloning in the spontaneously hypertensive rat. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  48. Kato N, Liang Y-Q, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  49. Ochiai Y, Liang Y-Q, Serizawa M, Birukawa N, Jesmin S, Kato N. Exploration of adipose tissue transcriptome network triggered in vivo by an insulin sensitizing agent, pioglitazone. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  50. Serizawa M, Liang Y-Q, Yanai K, Ochiai Y, Birukawa N, Jesmin S, Kato N. Compartmentalization of genome network downstream of the glucocorticoid receptor in cultured insulinoma cells and hepatoma cell. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  51. Manabe N, Hoshino A, Liang Y-Q, Fujioka K, Kato N, Yamamoto K. Quantum dot as a drug-tracer in vivo. Third International Conference on Advanced Materials and Nanotechnology, Wellington, New Zealand, February, 2007.
  52. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. American Heart Association, Scientific Sessions 2006, Chicago, IL, November, 2006.
  53. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Systematic expression profiling in the major end-organs after pharmacological intervention. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  54. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  55. Kato N, Yanai K, Makaya M, Nabika T, Katsuya T, Fujioka A, Yasuda K, Yamori Y, Kobayashi S, Ogihara T, Yazaki Y. Integrative large-scale candidate gene analysis of atherosclerotic diseases. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  56. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  57. Kohara Y, Inomata H, Liang Y-Q, Y Ochiai Y, Serizawa M, Yanai K, Kato N. Unraveling genetic susceptibility by constructing 14 consomic strains derived from the spontaneously hypertensive rat strains. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  58. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the japanese general population. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  59. Inomata H, Yanai K, Nabika T, Nagano S, Isobe M, Kobayashi S, Kato N. Large-scale genetic analysis of stroke in the Japanese. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  60. Inomata H, Liang YQ, Yanai K, Isobe M, Kato N. Unraveling genetic susceptibility by the construction of eight consomic strains derived from the stroke-prone spontaneously hypertensive rat. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  61. Manabe N, Hoshino A, Liang Y-Q, Goto T Kato N, Yamamoto K. Quantum dots conjugated with captoril while remained effective in vivo. 2nd International Conference on Advanced Materials and Nanotechnology, Queenstown, February, 2005.