研究業績

I. 英文原著論文(*corresponding author)

2017年

  1. Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P, Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA, Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD; EPIC-CVD Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M, Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M, Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med. 2017 Sep 12;14(9):e1002383. PMID: 28898252
  2. Nomura A, Won HH, Khera AV, Takeuchi F, Ito K, McCarthy S, Emdin CA, Klarin D, Natarajan P, Zekavat SM, Gupta N, Peloso GM, Borecki IB, Teslovich TM, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartze DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Juang JJ, Hsiung CA, Lin SY, Wang JS, Tada H, Kawashiri MA, Inazu A, Yamagishi M, Katsuya T, Nakashima E, Nakatochi M, Yamamoto K, Yokota M, Momozawa Y, Rotter JI, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer CJ, Abecasis GR, Saleheen D, Kubo M, Kato N, Ida Chen YD, Dewey FE, Kathiresan S. Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease. Circ Res. 2017 Jun 23;121(1):81-88. PMID: 28506971
  3. Niriella MA, Pathmeswaran A, De Silva ST, Kasturiratna A, Perera R, Subasinghe CE, Kodisinghe K, Piyaratna C, Rishikesawan V, Dassanayaka AS, De Silva AP, Wickramasinghe R, Takeuchi F, Kato N, de Silva HJ. Incidence and risk factors for non-alcoholic fatty liver disease: A 7-year follow-up study among urban, adult Sri Lankans. Liver Int. 2017 May 19. doi: 10.1111/liv.13478. [Epub ahead of print] PMID: 28544258
  4. Spracklen CN, Chen P, Kim YJ, Wang X, Cai H, Li S, Long J, Wu Y, Wang YX, Takeuchi F, Wu JY, Jung KJ, Hu C, Akiyama K, Zhang Y, Moon S, Johnson TA, Li H, Dorajoo R, He M, Cannon ME, Roman TS, Salfati E, Lin KH, Guo X, Sheu WH, Absher D, Adair LS, Assimes TL, Aung T, Cai Q, Chang LC, Chen CH, Chien LH, Chuang LM, Chuang SC, Du S, Fan Q, Fann CS, Feranil AB, Friedlander Y, Gordon-Larsen P, Gu D, Gui L, Guo Z, Heng CK, Hixson J, Hou X, Hsiung CA, Hu Y, Hwang MY, Hwu CM, Isono M, Juang JJ, Khor CC, Kim YK, Koh WP, Kubo M, Lee IT, Lee SJ, Lee WJ, Liang KW, Lim B, Lim SH, Liu J, Nabika T, Pan WH, Peng H, Quertermous T, Sabanayagam C, Sandow K, Shi J, Sun L, Tan PC, Tan SP, Taylor KD, Teo YY, Toh SA, Tsunoda T, van Dam RM, Wang A, Wang F, Wang J, Wei WB, Xiang YB, Yao J, Yuan JM, Zhang R, Zhao W, Chen YI, Rich SS, Rotter JI, Wang TD, Wu T, Lin X, Han BG, Tanaka T, Cho YS, Katsuya T, Jia W, Jee SH, Chen YT, Kato N, Jonas JB, Cheng CY, Shu XO, He J, Zheng W, Wong TY, Huang W, Kim BJ, Tai ES, Mohlke KL, Sim X. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet. 2017 May 1;26(9):1770-1784. PMID: 28334899
  5. Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJ, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses; BIOS Consortium; Lifelines Cohort Study; Understanding Society Scientific group; CHD Exome+ Consortium; ExomeBP Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium, Barnes MR, Tzoulaki I, Caulfield MJ, Elliott P; UK Biobank CardioMetabolic Consortium BP working group. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet. 2017 Mar;49(3):403-415. PMID: 28135244
  6. Liu X, Lu D, Saw WY, Shaw PJ, Wangkumhang P, Ngamphiw C, Fucharoen S, Lert-Itthiporn W, Chin-Inmanu K, Chau TN, Anders K, Kasturiratne A, de Silva HJ, Katsuya T, Kimura R, Nabika T, Ohkubo T, Tabara Y, Takeuchi F, Yamamoto K, Yokota M, Mamatyusupu D, Yang W, Chung YJ, Jin L, Hoh BP, Wickremasinghe AR, Ong RH, Khor CC, Dunstan SJ, Simmons C, Tongsima S, Suriyaphol P, Kato N, Xu S, Teo YY. Characterising private and shared signatures of positive selection in 37 Asian populations. Eur J Hum Genet. 2017 Apr;25(4):499-508. PMID: 28098149
  7. Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder MJ, Brosch M, Carstensen-Kirberg M, de Craen AJ, de Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco OH, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom PE, Soininen P, Stolk L, Strauch K, Tai ES, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JB, Vineis P, Wickremasinghe AR, Wijmenga C, Yang TP, Yuan W, Zhernakova A, Batterham RL, Smith GD, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Järvelin MR, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT, Matullo G, Gieger C, Kooner JS, Grallert H, Chambers JC. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature. 2017 Jan 5;541(7635):81-86. PMID: 28002404
  8. Gregson JM, Freitag DF, Surendran P, Stitziel NO, Chowdhury R, Burgess S, Kaptoge S, Gao P, Staley JR, Willeit P, Nielsen SF, Caslake M, Trompet S, Polfus LM, Kuulasmaa K, Kontto J, Perola M, Blankenberg S, Veronesi G, Gianfagna F, Männistö S, Kimura A, Lin H, Reilly DF, Gorski M, Mijatovic V; CKDGen consortium., Munroe PB, Ehret GB; International Consortium for Blood Pressure., Thompson A, Uria-Nickelsen M, Malarstig A, Dehghan A; CHARGE inflammation working group., Vogt TF, Sasaoka T, Takeuchi F, Kato N, Yamada Y, Kee F, Müller-Nurasyid M, Ferrières J, Arveiler D, Amouyel P, Salomaa V, Boerwinkle E, Thompson SG, Ford I, Wouter Jukema J, Sattar N, Packard CJ, Shafi Majumder AA, Alam DS, Deloukas P, Schunkert H, Samani NJ, Kathiresan S; MICAD Exome consortium., Nordestgaard BG, Saleheen D, Howson JM, Di Angelantonio E, Butterworth AS, Danesh J; EPIC-CVD consortium and the CHD Exome+ consortium. Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles. Eur J Prev Cardiol. 2017 Mar;24(5):492-504. PMID: 27940953

2016年

  1. Suzuki T, Zeng Z, Zhao B, Wei Z, Tanabe M, Shimbo T, Kajio H, Kato N, Naruse M. Comparison of coronary heart disease risk among four diagnostic definitions of metabolic syndrome. J Endocrinol Invest. 2016 Nov;39(11):1337-1346. PMID: 27572249
  2. Kawamura R, Tabara Y, Tsukada A, Igase M, Ohashi J, Yamada R, Takata Y, Kawamoto R, Saito I, Onuma H, Tanigawa T, Yamada K, Kato N, Ohyagi Y, Miki T, Kohara K, Osawa H. A genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population. Physiol Genomics. 2016 Sep 23: [Epub ahead of print] PMID: 27664181
  3. Sugiyama K, Sasano T, Kurokawa J, Takahashi K, Okamura T, Kato N, Isobe M, Furukawa T. Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice. Int Heart J. 2016 May 25;57(3):341-9. PMID: 27170476
  4. Ranawaka UK, Wijekoon CN, Pathmeswaran A, Kasturiratne A, Gunasekera D, Chackrewarthy S, Kato N, Wickremasinghe AR. Risk estimates of cardiovascular diseases in a Sri Lankan community. Ceylon Med J. 2016;61:11-7. PMID: 27031973
  5. Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 May 15;25(10):2070-2081. PMID: 26911676
  6. Wen W, Kato N, Hwang JY, Guo X, Tabara Y, Li H, Dorajoo R, Yang X, Tsai FJ, Li S, Wu Y, Wu T, Kim S, Guo X, Liang J, Shungin D, Adair LS, Akiyama K, Allison M, Cai Q, Chang LC, Chen CH, Chen YT, Cho YS, Choi BY, Gao Y, Go MJ, Gu D, Han BG, He M, Hixson JE, Hu Y, Huang T, Isono M, Jung KJ, Kang D, Kim YJ, Kita Y, Lee J, Lee NR, Lee J, Wang Y, Liu JJ, Long J, Moon S, Nakamura Y, Nakatochi M, Ohnaka K, Rao D, Shi J, Sull JW, Tan A, Ueshima H, Wu C, Xiang YB, Yamamoto K, Yao J, Ye X, Yokota M, Zhang X, Zheng Y, Qi L, Rotter JI, Jee SH, Lin D, Mohlke KL, He J, Mo Z, Wu JY, Tai ES, Lin X, Miki T, Kim BJ, Takeuchi F, Zheng W, Shu XO. Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Sci Rep. 2016 Jan 20;6:17958. PMID: 26785701
  7.  

2015年

  1. Saw W-Y, Liu X, Khor C-C, Takeuchi F, Katsuya T, Kimura R, Nabika T, Ohkubo T, Tabara Y, Yamamoto K, Yokota M, Japanese Genome Variation consortium, Teo Y-Y, Kato N. Mapping the genetic diversity of HLA haplotypes in the Japanese populations. Sci Rep. 2015 Dec 9;5:17855. PMID: 26648100
  2. Kato N*, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Leach IM, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Mok ZY, Nakatochi M, Sapari NS, Saxena R, Stewart AF, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Bryan MS, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LL, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Liewald DC, Matsubara T, Matsushita Y, Meitinger T, Mihailov E, Milani L, Mills R, Mononen N, Müller-Nurasyid M, Nabika T, Nakashima E, Ng HK, Nikus K, Nutile T, Ohkubo T, Ohnaka K, Parish S, Paternoster L, Peng H, Peters A, Pham ST, Pinidiyapathirage MJ, Rahman M, Rakugi H, Rolandsson O, Rozario MA, Ruggiero D, Sala CF, Sarju R, Shimokawa K, Snieder H, Sparsø T, Spiering W, Starr JM, Stott DJ, Stram DO, Sugiyama T, Szymczak S, Tang WH, Tong L, Trompet S, Turjanmaa V, Ueshima H, Uitterlinden AG, Umemura S, Vaarasmaki M, van Dam RM, van Gilst WH, van Veldhuisen DJ, Viikari JS, Waldenberger M, Wang Y, Wang A, Wilson R, Wong TY, Xiang YB, Yamaguchi S, Ye X, Young RD, Young TL, Yuan JM, Zhou X, Asselbergs FW, Ciullo M, Clarke R, Deloukas P, Franke A, Franks PW, Franks S, Friedlander Y, Gross MD, Guo Z, Hansen T, Jarvelin MR, Jørgensen T, Jukema JW, Kähönen M, Kajio H, Kivimaki M, Lee JY, Lehtimäki T, Linneberg A, Miki T, Pedersen O, Samani NJ, Sørensen TI, Takayanagi R, Toniolo D; BIOS-consortium; CARDIo GRAMplusCD; LifeLines Cohort Study; InterAct Consortium, Ahsan H, Allayee H, Chen YT, Danesh J, Deary IJ, Franco OH, Franke L, Heijman BT, Holbrook JD, Isaacs A, Kim BJ, Lin X, Liu J, März W, Metspalu A, Mohlke KL, Sanghera DK, Shu XO, van Meurs JB, Vithana E, Wickremasinghe AR, Wijmenga C, Wolffenbuttel BH, Yokota M, Zheng W, Zhu D, Vineis P, Kyrtopoulos SA, Kleinjans JC, McCarthy MI, Soong R, Gieger C, Scott J, Teo YY, He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat Genet. 2015 Nov;47(11):1282-93. PMID: 26390057
  3. Deng L, Hoh B-P, Lu D, Saw W-Y, Ong R T-H, Kasturiratne A, de Silva HJ, Zilfalil BA, Kato N, Wickremasinghe AR, TeoY-Y, Xu S. Dissecting the genetic structure and admixture of four geographical Malay populations. Sci Rep. 2015 Sep 23;5:14375. PMID: 26395220
  4. Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V, Wahl S, Elliott HR, Rota F, Scott WR, Zhang W, Tan ST, Campanella G, Chadeau-Hyam M, Yengo L, Richmond RC, Adamowicz-Brice M, Afzal U, Bozaoglu K, Mok ZY, Ng HK, Pattou F, Prokisch H, Rozario MA, Tarantini L, Abbott J, Ala-Korpela M, Albetti B, Ammerpohl O, Bertazzi PA, Blancher C, Caiazzo R, Danesh J, Gaunt TR, de Lusignan S, Gieger C, Illig T, Jha S, Jones S, Jowett J, Kangas AJ, Kasturiratne A, Kato N, Kotea N, Kowlessur S, Pitkäniemi J, Punjabi P, Saleheen D, Schafmayer C, Soininen P, Tai ES, Thorand B, Tuomilehto J, Wickremasinghe AR, Kyrtopoulos SA, Aitman TJ, Herder C, Hampe J, Cauchi S, Relton CL, Froguel P, Soong R, Vineis P, Jarvelin MR, Scott J, Grallert H, Bollati V, Elliott P, McCarthy MI, Kooner JS. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endocrinol. 2015 Jul;3(7):526-34. PMID: 26095709
  5. Akiyama K, Liang YQ, Isono M, Kato N*. Investigation of Functional Genes at Homologous Loci Identified Based on Genome-wide Association Studies of Blood Lipids via High-fat Diet Intervention in Rats using an in vivo Approach. J Atheroscler Thromb. 2015 May 20;22(5):455-80. PMID: 25445557
  6. Takeuchi F, Isono M, Yamamoto K, Yokota M, Akiyama K, Katsuya T, Kim H-S, Park JE, Jang Y, Lee Ji-Y, AGEN Consortium, Lee J-Y, Kato N*. Heterogeneous effects of association between blood pressure loci and coronary artery disease in east Asian individuals.Circ J. 2015 Mar 25;79(4):830-8. PMID: 25740055
  7. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 2015 Mar 15;24(6):1791-800. PMID: 25429064
  8. Kasturiratne A, Akiyama K, Niriella MA, Takeuchi F, Isono M, Dassanayake AS, De Silva AP, Wickremasinghe RA, Kato N, de Silva HJ. Association of genetic variants with non-alcoholic fatty liver disease in an urban Sri Lankan community Liver Int. 2015 Feb;35(2):676-9. PMID: 24947803
  9. Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Hee Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Tomohiro K, Oh J, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung K, Nabika T, Bae JB, Lee M, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ. Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. Diabetes. 2015 Jan;64(1):291-8. PMID: 25187374

2014年

  1. Akiyama K, Takeuchi F, Isono M, Chakrawarthy S, Nguyen QN, Wen W, Yamamoto K, Katsuya T, Kasturiratne A, Pham ST, Zheng W, Matsushita Y, Kishimoto M, Do LD, Shu XO, Wickremasinghe AR, Kajio H, Kato N*. Systematic Fine-Mapping of Association with BMI and Type 2 Diabetes at the FTO Locus by Integrating Results from Multiple Ethnic Groups. PLoS One. 2014 Jun 30;9(6):e101329. PMID: 24978468
  2. Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, Shimizu Y, Hosaka T, Goto M, Kato N, Okamura T, Suematsu M, Yokoyama S, Toyama-Sorimachi N. The Histidine Transporter SLC15A4 Coordinates mTOR-Dependent Inflammatory Responses and Pathogenic Antibody Production. Immunity. 2014 Sep 18;41(3):375-88. PMID: 25238095
  3. Kim YK, Kim Y, Hwang MY, Shimokawa K, Won S, Kato N, Tabara Y, Yokota M, Han BG, Lee JH, Kim BJ. Identification of a genetic variant at 2q12.1 associated with blood pressure in East-Asians by genome-wide scan including gene-environment interactions.BMC Med Genet. 2014 Jun 5;15(1):65. PMID: 24903457
  4. Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T. Meta-analysis of genome-wide Hum Mol Genet. 2014 Oct 15;23(20):5492-504 PMID: 24861553
  5. Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi MO, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Huey-Herng Sheu W, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T; Hematology CHARGE Group Working, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES. Multiple Non-glycemic Genomic Loci Are Newly Associated with Blood Level of Glycated Hemoglobin in East Asians. Diabetes. 2014 Jul;63(7):2551-62. PMID: 24647736
  6. Xi B, Takeuchi F, Meirhaeghe A, Kato N, Chambers JC, Morris AP, Cho YS, Zhang W, Mohlke KL, Kooner JS, Shu XO, Pan H, Tai ES, Pan H, Wu JY, Zhou D, Chandak GR; DIAGRAM Consortium; AGEN-T2D consortium; SAT2D Consortium. Associations of genetic variants in/near BMI-associated genes with type 2 diabetes: A systematic meta-analysis. Clin Endocrinol (Oxf). 2014 Nov;81(5):702-10. PMID: 24528214
  7. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium & Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44. PMID: 24509480
  8. Aoyama-Mani C, Kawachi S, Ogawa Y, Kato N*. Vascular complications and coagulation-related changes in the perioperative period in Japanese patients undergoing non-cardiac surgery. J Atheroscler Thromb. 2014;21(5):414-34. PMID: 24351790
  9. Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet. 2014 Feb 15;23(4):1108-19. PMID: 24105470

2013年

  1. Kato N*. Candidate genes revisited in the genetics of hypertension and blood pressure. Hypertens Res. 2013 Dec;36(12):1032-4. PMID: 23945960
  2. Kelly TN, Takeuchi F, Tabara Y, Edwards TL, Kim YJ, Chen P, Li H, Wu Y, Yang CF, Zhang Y, Gu D, Katsuya T, Ohkubo T, Gao YT, Go MJ, Teo YY, Lu L, Lee NR, Chang LC, Peng H, Zhao Q, Nakashima E, Kita Y, Shu XO, Kim NH, Tai ES, Wang Y, Adair LS, Chen CH, Zhang S, Li C, Nabika T, Umemura S, Cai Q, Cho YS, Wong TY, Zhu J, Wu JY, Gao X, Hixson JE, Cai H, Lee J, Cheng CY, Rao DC, Xiang YB, Cho MC, Han BG, Wang A, Tsai FJ, Mohlke K, Lin X, Ikram MK, Lee JY, Zheng W, Tetsuro M, Kato N, He J. Genome-Wide Association Study Meta-Analysis Reveals Transethnic Replication of Mean Arterial and Pulse Pressure Loci. Hypertension. 2013 Nov;62(5):853-9. PMID: 24001895
  3. Kato N*. Insights into the genetic basis of type 2 diabetes. J Diabetes Invest. 2013 May;4(3):233-44.
  4. Wang X, Chua HX, Chen P, Ong RT, Sim X, Zhang W, Takeuchi F, Liu X, Khor CC, Tay WT, Cheng CY, Suo C, Liu J, Aung T, Chia KS, Kooner JS, Chambers JC, Wong TY, Tai ES, Kato N, Teo YY. Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies. Hum Mol Genet. 2013 Jun 1;22(11):2303-11. PMID: 23406875
  5. Takeuchi F, Yamamoto K, Isono M, Katsuya T, Akiyama K, Ohnaka K, Rakugi H, Yamori Y, Ogihara T, Takayanagi R, Kato N*. Genetic impacts on uric acid concentration and hyperuricemia in the Japanese population. J Atheroscler Thromb. 2013;20(4):351-67. PMID: 23238572
  6. Chackrewarthy S, Gunasekera D, Pathmeswaren A, Wijekoon CN, Ranawaka UK, Kato N, Takeuchi F, Wickremasinghe AR. A Comparison between Revised NCEP ATP III and IDF Definitions in Diagnosing Metabolic Syndrome in an Urban Sri Lankan Population: The Ragama Health Study. ISRN Endocrinol. 2013;2013:320176. PMID: 23533799
  7. Pinidiyapathirage MJ, Kasturiratne A, Ranawaka UK, Gunasekara D, Wijekoon N, Medagoda K, Perera S, Takeuchi F, Kato N, Warnakulasuriya T, Wickremasinghe AR.The burden of diabetes mellitus and impaired fasting glucose in an urban population of Sri Lanka. Diabetic Med. 2013 Mar;30(3):326-32. PMID: 22998091
  8. Kasturiratne A, Weerasinghe S, Dassanayake AS, Rajindrajith S, de Silva AP, Kato N, Wickremasinghe AR, de Silva HJ. Influence of non-alcoholic fatty liver disease on the development of diabetes mellitus. J Gastroenterol Hepatol. 2013 Jan;28(1):142-7. PMID: 22989165

2012年

  1. Okamura T, Yanobu-Takanashi R, Takeuchi F, Isono M, Akiyama K, Shimizu Y, Goto M, Liang Y-Q, Yamamoto K, Katsuya T, Fujioka A, Ohnaka K, Takayanagi R, Ogihara T, Yamori Y, Kato N*. Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes. PLoS One. 2012;7(11):e49055. PMID: 23173044
  2. Takeuchi F, Isono M, Katsuya T, Yokota M, Yamamoto K, Nabika T, Shimokawa K, Nakashima E, Sugiyama T, Rakugi H, Yamaguchi S, Ogihara T, Yamori Y, Kato N*. Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. PLoS One. 2012;7(9):e46385. PMID: 23050023
  3. Muhihi A, Njelekela M, Mpembeni R, Masesa Z, Kitamori K, Mori M, Kato N, Mtabaji J, Yamori Y. Physical activity and cardiovascular disease risk factors among young and middle-aged men in urban Mwanza, Tanzania. Pan Afr Med J. 2012;11:11. PMID: 22368754
  4. Xi B, Takeuchi F, Chandak GR, Kato N, Pan HW; AGEN-T2D Consortium, Zhou DH, Pan HY, Mi J. Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals. Diabetologia. 2012 Oct;55(10):2660-6. PMID: 22869321
  5. Takeuchi F, Yamamoto K, Katsuya T, Sugiyama T, Nabika T, Ohnaka K, Yamaguchi S, Takayanagi R, Ogihara T, Kato N*. Reevaluation of blood pressure and hypertension association with seven candidate genes by replication study and meta-analysis with larger sample size. Hypertens Res. 2012 Aug;35(8):825-31. PMID: 22456346
  6. Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; The KidneyGen Consortium; The CKDGen Consortium, Albrecht E; The GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature Genet. 2012 Jul 15;44(8):904-909. PMID: 22797727
  7. Kato N*. Ethnic diversity in type 2 diabetes genetics between East Asians and Europeans. J Diabetes Invest. 2012 Aug;3(4):349-351.
  8. Kato N*. Ethnic differences in genetic predisposition to hypertension. Hypertens Res. 2012 Jun;35(6):574-81. PMID: 22476227
  9. Li H, Kilpelainen T, Liu C, Zhu J, Liu Y, Hu C, Yang Z, Bao W, Cha S, Wu Y, Yang T-L, Sekine A, Choi BY, Yajnik CS, Zhou D, Takeuchi F, Yamamoto K, Chan JC, Mani KR, Been LF, Imamura M, Nakashima E, Lee N, Fujisawa T, Karasawa S, Wen W, Lu W, Chang Y-C, Xiang Y-B, Gao Y, Liu S, Song Y, Kwak SH, Shin HD, Park KS, Fall C, Kim JY, Sham PC, Lam KSL, Zheng W, Shu XO, Deng H-W, Ikegami H, Sanghera DK, Chuang L-M, Liegang Liu, Hu R, Kim Y-M, Daimon M, Hotta K, Jia W, Kooner JS, Chambers JC, Chandak GR, Ma RC, Maeda S, Dorajoo R, Yokota M, Takayanagi R, Kato N, Lin X, Loos RJF. Association of genetic variation in FTO with risk of obesity and type 2 diabetes in up to 96,551 East and South Asians. Diabetologia. 2012 Apr;55(4):981-95. PMID: 22109280
  10. Okada Y, Kubo M, Ohmiya H, Takahashi A, Kumasaka N, Hosono N, Maeda S, Wen W, Dorajoo R, Go MJ, Zheng W, Kato N, Wu J-Y, Lu Q, GIANT consortium, Tsunoda T, Yamamoto K, Nakamura Y, Kamatani N, Tanaka T. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nature Genet. 2012 Feb 19;44(3):302-6. PMID: 22344221
  11. Wen W, Cho Y-S, Zheng W, Dorajoo R, Kato N, Lu Q, Chen C-H, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao Y-T, Saw S-M, Go M-J, Takeuchi F, Chang L-C, Kokubo Y, Liang J, Hao M, Marchand LL, Zhang Y, Hu Y, Wong T-Y, Long J, Han B-G, Kubo M, Yamamoto K, Su M-H, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP-K, Cai Q, Tsunoda T, Tsai F-J, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang Y-B, Maeda S, Ong RTH, Li C, Nakamura Y, Aung T, Kamatani N, Liu J-J, Lu W, Yokota M, Seielstad M, Fann CSJ, The Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu J-Y, Lee J-Y, Hu FB, Tanaka T, Tai ES, Shu X-O. Meta-analysis identifies common variants associated with body mass index in east Asians. Nature Genet. 2012 Feb 19;44(3):307-311. PMID: 22344219

2011年

  1. Cho YS, Chen C-H, Hu C, Long J, Ong RTH, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang Y-C, Kwak SH, Ma RCW, Yamamoto K, Adair LS, Aung T, Cai Q, Chang L-C, Chen Y-T, Gao Y, Hu FB, Kim H-L, Kim S, Kim YJ, Lee JJ-M, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, NgDP-K, Tay WT, Tsai F-J, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang T-J, Bao Y, Hedman AK, P Morris AP, McCarthy MI, DIAGRAM consortium36, MuTHER consortium36, Takayanagi R, Park KS, Jia W, Chuang L-M, ChanJCN, Maeda S, Kadowaki T, Lee J-Y, Wu J-Y, TeoYY, Tai ES, Shu XO, Mohlke KL, Kato N, Han B-G, Seielstad M. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet. Dec 11;44(1):67-72. PMID: 22158537
  2. Kato N*, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS, He J. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet. 2011, Jun;43(6):531-8. PMID: 21572416
  3. Kooner JS*, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, Been LF, Chia K-S, Dimas AS, Hassanali N, Jafar T, Jowett JBM, Venkatesan R, Rees SD, Takeuchi F, Young R, Aung T, Basit A, Chidambaram M, Das D, Grunberg E, Hedman AK, Hydrie ZI, Islam M, Khor C-C, Kowlessur S, Kristensen MM, Liju S, Lim W-Y, Matthews DR, Liu J, Morris AP, Nica AC, Pinidiyapathirage JM, Prokopenko I, Rasheed A, Samuel M, Shah N, Shera AS, Small KS, Suo C, Wickremasinghe AR, Wong TY, Yang M, Zhang F, DIAGRAM, MuTHER, Abecasis GR, Barnett AH, Caulfield M, Deloukas P, Frayling T, Froguel P, Kato N, Katulanda P, Kelly MA, Liang J, Mohan V, Sanghera DK, Scott J, Seielstad M, Zimmet PZ, Elliott P, Teo YY, McCarthy MI, Danesh J, Tai ES, Chambers JC*. Genome-wide association study in people of South Asian ancestry identifies six novel susceptibility loci for Type 2 Diabetes. Nat Genet. Aug 28;43(10):984-9. PMID: 21874001
  4. Takeuchi F*, Kobayashi S, Ogihara T, Fujioka A, Kato N. Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. Genome Res. 2011, Jul;21(7):1122-30. PMID: 21441355
  5. Njelekela M, Muhihi A*, Mpembeni R, Masesa Z, Kitamori K, Mori-Yamori M, Kato N, Mtabaji J, Yamori Y. Prevalence of Cardiovascular Disease Risk Factors among Young and Middle-age Men in Urban Mwanza, Tanzania. J Public Health. 2011, 19(6):553-61.
  6. Takeuchi F, Yamamoto K, Katsuya T, Nabika T, Sugiyama T, Fujioka A, Isono M, Ohnaka K, Fujisawa T, Nakashima E, Ikegami H, Nakamura J, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Takayanagi R, Kato N*. Association of obesity susceptibility genetic variants with type 2 diabetes in the Japanese. Diabetologia. 2011, 54(6):1350-9. PMID: 21369819
  7. Dassanayake AS, Kasturiratne A, Niriella MA, Kalubovila U, Rajindrajith S, De Silva AP, Kato N, Wickremasinghe R and de Silva J*. Prevalence of acanthosis nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome. BMC Research Notes. 2011, 4(1):25. PMID: 21276250
  8. Sasawatari S, Okamura T, Kasumi E, Tanaka-Furuyama K, Yanobu-Takanashi R, Shirasawa S, Kato N, Toyama-Sorimachi N*. The solute carrier family 15A4 regulates TLR9 and NOD1 functions in the innate immune system and promotes colitis in mice. Gastroenterology. Jan 26. 2011, 140(5):1513-25. PMID: 21277849
  9. Takeuchi F, Isono M, Nabika T, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Ogihara T, Yamori Y, Fujioka A, Kato N*. Confirmation of ALDH2 as a major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in Japanese. Circ J. 2011, 75(4):911-8. PMID: 21372407

2010年

  1. Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S. Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS One. 2010 Dec 9;5(12):e15553. PMID: 21151568
  2. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N*. Blood pressure and hypertension are associated with seven loci showing male-specific interaction with age among the Japanese. Circulation. 2010, 121(21):2302-9. PMID: 20479155
  3. Takeuchi F, Kashida M, Okazaki O, Tanaka Y, Fukuda S, Kashima T, Hosaka S, Hiroe M, Kimura S, Kato N*. Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients. Circ J. 2010, 74:977-82. PMID: 20339191
  4. Taniguchi-Yanai K, Koike Y, Hasegawa T, Furuta Y, Serizawa M, Ohshima N, Kato N*, Yanai K*. Identification and characterization of glucocorticoid receptor-binding sites in the human genome. J Recept Signal Transduct Res. 2010, 30(2):88-105. PMID: 20163328
  5. Takeuchi F, Katsuya T, Charkrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N*. Common variants at the GCK, GCKR, G6PC2-ABCB11,and MTNR1B lociare associatedwith fasting glucose in two Asian populations. Diabetologia. 2010, 53(2):299-308. PMID: 19937311

2009年

  1. Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N*. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes. 2009, 58(7):1690-9. PMID: 19401414
  2. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Makino Y, Wakahara S, Inoki I, Miyamori I, Pinet F; the Genomic Disease Outcome Consortium (G-DOC) Study Investigators. Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blocker. Diabetes Care. 2009, 32(8):1485-90. PMID: 19509012
  3. Takeuchi F, Nabika T, Isono M, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Yamori Y, Ogihara T, Kato N*. Evaluation of genetic loci influencing adult height in the Japanese population. J Hum Genet. 2009, 54(12):749-52. PMID: 19834501
  4. Tsuchihashi-Makaya M, Serizawa M, Yanai K, Katsuya T, Takeuchi F, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environmental interaction regarding alcohol metabolizing enzymes in the Japanese general population. Hypertens Res. 2009, 32(3):207-13. PMID: 19262484
  5. Fujimoto T, Miyasaka K, Koyanagi M, Tsunoda T, Baba I, Doi K, Ohta M, Kato N, Sasazuki T, Shirasawa S. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS ONE. 2009, 4:e4240. Epub 2009 Jan 21. PMID: 19156225
  6. Tsuchihashi-Makaya M, Hamaguchi S, Kinugawa S, Yokota T, Goto D, Yokoshiki H, Kato N, Takeshita A, Tsutsui H; JCARE-CARD Investigators. Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J. 2009, 73(10):1893-900. PMID: 19644216
  7. Dassanayake AS, Kasthuriratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, Makaya M, Mizoue T, Kato N, Wickremasinghe AR, de Silva HJ. Prevalence and risk factors for non-alcoholic fatty liver disease (NAFLD) among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009, 24(7):1284-8. PMID: 19476560
  8. Morii T, Ohno Y, Kato N, Hirose H, Kawabe H, Hirao K, Eguchi T, Maruyama T, Hayashi M, Saito I, Yazaki Y, Saruta T. CD36 SNP is associated with variation in LDL-cholesterol in young Japanese men. Biomarkers. 2009, 14(4):207-12. PMID: 19489681
  9. Tsuchihashi-Makaya M, Kato N, Chishaki A, Takeshita A, Tsutsui H. Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure. Circ J. 2009, 73(2):280-7. PMID: 19096191
  10. Tsukahara T, Nakashima E, Watarai A, Hamada Y, Naruse K, Kamiya H, Nakamura N, Kato N, Hamajima N, Sekido Y, Niwa T, Tomita M, Oiso Y, Nakamura J. Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients. Diabetes Res Clin Pract. 2009, 84(2):179-86. PMID: 19269054
  11. Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H. Fas Promoter Region Gene Polymorphism Is Associated With An Increased Risk For Myocardial Infarction. Hypertens Res. 2009, 32(4):261-4. PMID: 19262492
  12. Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 2009 Mar;5(3):e1000433. Epub 2009 Mar 20. PMID: 19300499

2008年

  1. Kato N*, Miyata T, Tabara Y, Katsuya T, Yanai K, Hanada H, Kamide K, Nakura J, Kohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakayama T, Soma M, Hata A, Fujioka A, Kawano Y, Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara T, Sugano S, Miki T, Tomoike H. High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet. 2008, 17:617-27. PMID: 18003638
  2. Ochiai Y, Liang YQ, Serizawa M, Kato N*. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. Physiol Genomics. 2008, 35:330-40. PMID: 18796534
  3. Takeuchi F, Ochiai Y, Serizawa M, Yanai K, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q. J Hum Genet. 2008, 53:314-24. PMID: 18259684
  4. Takeuchi F, Serizawa M, Kato N*. HapMap coverage for SNPs in the Japanese population. J Hum Genet. 2008, 53:96-9. PMID: 18043864
  5. Serizawa M, Nabika T, Ochiai Y, Takahashi K, Yamaguchi S, Makaya M, Kobayashi S, Kato N*. Association between PRKCH gene polymorphisms and subcortical silent brain infarction. Atherosclerosis. 2008, 199:340-5. PMID: 18164711
  6. Kato N*, Liang YQ, Ochiai Y, Birukawa N, Serizawa M, Jesmin S. Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. Hypertens Res. 2008, 31:1963-75. PMID: 19015604
  7. Kato N*, Liang YQ, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. Eur J Pharmacol. 2008, 584:376-89. PMID: 18295756
  8. Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics. 2008, 91:451-7. PMID: 18329245

2007年

  1. Takeuchi F, Yanai K, Inomata H, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search of type 2 diabetes susceptibility gene on chromosome 20q. Biochem Biophys Res Commun. 2007, 357:1100-6. PMID: 17466274
  2. Jesmin S, Maeda S, Mowa CN, Zaedi S, Togashi H, Prodhan SH, Yamaguchi T, Yoshioka M, Sakuma I, Miyauchi T, Kato N. Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat. Eur J Pharmacol. 2007, 574:158-71. PMID: 17689527
  3. Fujimoto T, Koyanagi M, Baba I, Nakabayashi K, Kato N, Sasazuki T, Shirasawa S. Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J Hum Genet. 2007, 52:978-84. PMID: 17934691
  4. Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology. 2007, 148:2453-7. PMID: 17303661

2006年

  1. Konoshita T, Wakahara S, Mizuno S, Motomura M, Aoyama C, Makino Y, Kawai Y, Kato N, Koni I, Miyamori I, Mabuchi H. Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. Diabetes Care. 2006, 29:848-52. PMID: 16567826
  2. Manabe N, Hoshino A, Liang YQ, Goto T, Kato N, Yamamoto K. Quantum dot as a drug tracer in vivo. IEEE Trans Nanobioscience. 2006, 5:263-7. PMID: 17181025
  3. Takeuchi F, Yamamoto K. Effectiveness of realistic vaccination strategies for contact networks of various degree distributions. J Theor Biol. 2006, 243(1):39-47. PMID: 16860340

2005年

  1. Takeuchi F, Yanai K, Morii T, Ishinaga Y, Taniguchi-Yanai K, Nagano S, Kato N. Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. Genetics. 2005, 170:291-304. PMID: 15716494
  2. Watanabe T, Iizuka Y, Liang Y-Q, Inomata H, Gotoda T, Yanai K, Isobe M, Kato N*. Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony Biochem Biophys Res Commun. 2005, 329: 879-87. PMID: 15752738
  3. Inomata H, Watanabe T, Iizuka Y, Liang Y-Q, Mashimo T, Nabika T, Ikeda K, Yanai K, Gotoda T, Yamori Y, Isobe M, Kato N*. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Hypertens Res. 2005, 28: 273-81. PMID: 16097372

II. 学術集会発表−国際学会・研究会

  1. Spracklen CN, Kim Y.J, Chen P, Sim X, Cai H, Li S, Long J, Wu Y, Wang X, Wang YX, Takeuchi F, Jung KJ, Wu JY, Johnson T.A, Li H, Dorajoo R, He M, Akiyama K, Zhang Y, Hou X, Hu C, Moon S, Salfati E, AGEN Consortium. Association analyses of up to 72,043 East Asian individuals and trans-ancestry analyses with up to 186,265 European individuals reveal new loci associated with cholesterol and triglyceride levels. 61st annual meeting of the American Society of Human Genetics, Vancouver, Canada, October, 2016.
  2. Niriella MA, De Silva ST, Kasturiratna A, Perera KR, Subasinghe SKCE, Kodisinghe SK, Piyaratna TACL, Vithiya K, Dassanayaka AS, De Silva AP, Pathmeswaran A, Wickramasinghe AR,Kato N, de Silva HJ. Lean non-alcoholic fatty liver disease (Lean-NAFLD): characteristics and risk factors from a community cohort follow up study. UEG week 2016, Vienna, Austria, October 2016.
  3. Kato N. DNA methylation and hypertension. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  4. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q,Kato N. Epigenetic changes in the brain with high-salt intervention in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  5. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q,Kato N. Epigenetic changes in the liver with high-fat-diet intervention in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  6. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q,Kato N. Epigenetic changes in the liver with dexamethasone administration in SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  7. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q,Kato N. Comparison of epigenetic changes in the liver between Tg-CETP rat and SHR. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  8. Shimizu-Furusawa H, Takeuchi F, Isono M, Akiyama K, Liang Y-Q,Kato N. Comparison of epigenetic changes in the liver between RNO4-derived congenic rat and progenitor strains. Cardiovascular Genetics, Satellite Symposium of ISH 2016. Tokyo, Japan, September 2016.
  9. Konoshita T, Sakai A, Kaeriyama S, Urabe M, Nakaya T, Yamada M, Ichikawa M, Sato S, Yamamoto K, Imagawa M, Fujii M, Zenimaru Y, Suzuki J, Makino Y, Ishizuka T,Kato N. Association study of angiotensinase A (ENPEP) genotype with diabetic nephropathy. 26th European Meeting on Hypertension and Cardiovascular Protection. Paris, France, June, 2016.
  10. Kato N. Genomic medicine in NCDs: findings from Asians/ South Asians to global collaboration. 25th Anniversary International Scientific Conference University of Kelaniya. Ragama, Sri Lanka, April 2016.
  11. Niriella M, Kasturiratna A, De Silva S, Perera R, Subasinghe C, Kodisinghe K, Piyarathna C, Rishikeshavan V, Dassanayake A, De Silva A, Pathmeswaran A,Kato N, de Silva J. Incidence and risk factors for non-alcoholic fatty liver disease in an urban, adult Sri Lankan population – a community cohort follow-up study. UEG week 2015, Barcelona, Spain, October 2015.
  12. Takeuchi F, Katsuya T, Kimura R, Nabika T, Okubo T, Tabara Y, Yamamoto K, Yokota M, Saw W-Y, Teo YY,Kato N. The fine-scale genetic structure of the Japanese population: estimation of genetic materials derived from Asians and the basis of genetic differentiation. 60th annual meeting of the American Society of Human Genetics, Baltimore, USA, October, 2015.
  13. Kawamura R, Tabara Y, Igase M, Takata Y, Kawamoto R, Saito I, Onuma H, Kohara K, Tanigawa T, Yamada K,Kato N, Miki M, Osawa H. Rs10401670 was identified as a possible functional quantitative trait locus for circulating resistin by a genome-wide association study in Japanese. 75th Scientific Session of American Diabetic Association. Boston, USA, June 2015.
  14. Loh M, et al. on behalf of iGEN-BP. Trans-ethnic genome-wide association study identifies 15 new genetic loci influencing blood pressure traits, and implicates a role for DNA methylation: the International Genetics of Blood Pressure (iGEN-BP) Study. 59th annual meeting of the American Society of Human Genetics, San Diego, USA, October, 2014.
  15. Kato N. Towards elucidation of pathological basis of intractable tumors. International Symposium on Pheochromocytoma and Paraganglioma 2014. Kyoto, Japan, September 2014.
  16. Kato N. Genetics of NAFLD/ NASH. 127th Anniversary International Medical Congress of Sri Lanka Medical Association. Colombo, Sri Lanka, July 2014.
  17. Kato N. Can rat genetics help to improve human genetics? Cardiovascular Genetics Satellite 2014. Rome, Italy, June 2014.
  18. Kawamura R, Tabara Y, Igase M, Takata Y, Kawamoto R, Saito I, Tanigawa T, Onuma H, Kohara K,Kato N, Miki M, Osawa H. Resistin SNP-358, SNP-420, and rs1423096 were identified as major quantitative trait loci for serum resistin by a genome-wide association study in Japanese. 74th Scientific Session of American Diabetic Association. San Francisco, USA, June 2014.
  19. Konoshita T, Yamada M, Ichikawa M, Sato S, Imagawa M, Makino Y, Fujii M, Wakahara S, Zenimaru Y, Arakawa K, Suzuki J,Kato N. Measurement of soluble angiotensin-IV receptor (s-AT4), identified through systemic transcriptome analysis of hypertensive and diabetic renal tissue. 23rd European Meeting on Hypertension and Cardiovascular Protection. Milan, Italy, June, 2013.
  20. Kato N. Global genomics of BP. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  21. Akiyama K, Liang Y-Q,Kato N. Evaluation of human lipid-associated genes and methylation in SHR fed on high lipid diet. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  22. Akiyama K, Liang Y-Q,Kato N. Identification of "neutralizing" gene-gene interaction in the regulation of blood pressure in the SHR-related strains. Exploration of genetic loci controlling serum cholesterol concentration in the SHR-related strains: identification of two novel cholesterol loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  23. Liang Y-Q, Akiyama K,Kato N. Exploration of genetic loci controlling serum cholesterol concentration in the SHR-related strains: identification of two novel cholesterol loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  24. Liang Y-Q, Akiyama K,Kato N. Exploration of cardiac hypertrophy loci in the SHR-related strains: confirmation of the endonuclease G locus and identification of novel loci. Cardiovascular Genetics Satellite 2012. Melbourne, Australia, September 2012.
  25. Konoshita T, Kimura T, Fujii M, Makino Y, Wakahara S, Inaba S, Miyamori I,Kato N. A systematic review of pharmacogenetics in the renin angiotensin system – the genetic variants and inter-individual variation in blood pressure response to the blocking agents. 22nd European Meeting on Hypertension and Cardiovascular Protection. London, UK, April, 2012.
  26. Matsushita Y, Kishimoto M, Takahashi Y, Kanagawa S, Noda M, Thai SP, Ngoc QN, Hong HPT, Doan LD, Lan VN, Zeng Z-P, Wickremasinghe AR, Naruse M,Kato N, Kajio H. The Cutoff Levels of Waist Circumference for Predicting the Presence of the Clustering of Metabolic Risk Factors in some Asian Populations. IDF World Diabetes Congress 2011, Dubai, UAE, December, 2011.
  27. Horikoshi M, Wiltshire S,Kato N, Asimit J, Rayner N, Robertson N, Takeuchi F, Mahajan A, Teo Y-Y, Zeggini E, Morris A, McCarthy M, T2D-GENES. Trans-ethnic fine-mapping of Type 2 Diabetes susceptibility loci using a “Cosmopolitan” reference panel for imputation. 61st annual meeting of the American Society of Human Genetics and the International Congress of Human Genetics 2011, Montreal, Canada, Oct 14, 2011.
  28. Kato N. GWAS of hypertension-associated disease in the Japanese. 20th KOGO Conference. Osong, Korea, September, 2011.
  29. Horikoshi M,Kato N, Wiltshire S, Asimit J, Rayner NW, Robertson N, Takeuchi F, Teo YY, Zeggini, E, McCarthy M, Morris A, T2D-GENES Consortium. Trans-Ethnic Fine-Mapping of T2D Susceptibility Loci. ADA Annual Meeting 2011, San Diego, USA, June, 2011.
  30. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. 5th Oriental Congress of Cardiology, Shanghai, China, May, 2011.
  31. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. The National University of Singapore, Advanced genomics symposium, Singapore, February, 2011.
  32. Takeuchi F,Kato N. Testing heterogeneity of quantitative trait variance among genotype classes guides fine mapping of association signals. 60th annual meeting of the American Society of Human Genetics, Washington DC, USA, November, 2010.
  33. Kato N. Genetic susceptibility to diabetes and associated diseases in the Japanese. 8th IDF WPR Congress. Busan, Korea, October, 2010.
  34. Kato N. Genome-wide exploration of genetic susceptibility to cardiometabolic diseases. International Congress of Pathophysiology & International SHR Symposium 2010. Montreal, Canada, September, 2010.
  35. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N. Blood pressure and hypertension are associated with seven loci in the Japanese population. 23rd Scientific Meeting International Society of Hypertension. Vancouver, Canada, September, 2010.
  36. Kato N. Genetic susceptibility to cardiovascular disease and its risk factors in the Japanese. 19th KOGO Conference. Seoul, Korea, September, 2010.
  37. Kato N. Risk of myocardial infarction and stroke among Asians. 10th South East Asia Regional Scientific Meeting of the International Epidemiological Association, Colombo, Sri Lanka, May, 2010.
  38. Takeuchi F, Katsuya T, Yamamoto K, Nabika T, Ranawaka U, Sugiyama T, Fujioka A, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Chakrewarthy S, Wickremasinghe R, andKato N, for the NIBIO GWA Study and Ragama Health Study. Confirmation of eight loci associated with measures of obesity in two Asian populations with substantial ethnic heterogeneity. 27th annual scientific meeting of the Obesity Society, Washington DC, USA, October, 2009.
  39. Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R,Kato N for the NIBIO GWA Study. Ethnic diversity in fine mapping of the susceptibility loci G6PC2-ABCB11 for fasting glucose and CDKAL1 for type 2 diabetes. 59th annual meeting of the American Society of Human Genetics, Honolulu, USA, October, 2009.
  40. Konoshita T,Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Kimura T, Fujii M, Makino Y, Wakahara S, Arakawa K, Inoki I, Miyamori I, Pinet P. Genetic Variant of the Renin Angiotensin System Influences Blood Pressure Response to Angiotensin Receptor Blocker. 19th European Meeting on Hypertension, Milan, Italy, June, 2009.
  41. Kato N, Liang Y-Q, Ochiai Y, Serizawa M. Dissection of phenotypic traits associated with metabolic syndrome and positional cloning in the spontaneously hypertensive rat. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  42. Kato N, Liang Y-Q, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  43. Ochiai Y, Liang Y-Q, Serizawa M, Birukawa N, Jesmin S,Kato N. Exploration of adipose tissue transcriptome network triggered in vivo by an insulin sensitizing agent, pioglitazone. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  44. Serizawa M, Liang Y-Q, Yanai K, Ochiai Y, Birukawa N, Jesmin S, Kato N. Compartmentalization of genome network downstream of the glucocorticoid receptor in cultured insulinoma cells and hepatoma cell. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  45. Manabe N, Hoshino A, Liang Y-Q, Fujioka K,Kato N, Yamamoto K. Quantum dot as a drug-tracer in vivo. Third International Conference on Advanced Materials and Nanotechnology, Wellington, New Zealand, February, 2007.
  46. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T,Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. American Heart Association, Scientific Sessions 2006, Chicago, IL, November, 2006.
  47. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K,Kato N. Systematic expression profiling in the major end-organs after pharmacological intervention. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  48. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T,Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  49. Kato N, Yanai K, Makaya M, Nabika T, Katsuya T, Fujioka A, Yasuda K, Yamori Y, Kobayashi S, Ogihara T, Yazaki Y. Integrative large-scale candidate gene analysis of atherosclerotic diseases. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  50. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K,Kato N. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  51. Kohara Y, Inomata H, Liang Y-Q, Y Ochiai Y, Serizawa M, Yanai K,Kato N. Unraveling genetic susceptibility by constructing 14 consomic strains derived from the spontaneously hypertensive rat strains. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  52. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T,Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the japanese general population. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  53. Inomata H, Yanai K, Nabika T, Nagano S, Isobe M, Kobayashi S,Kato N. Large-scale genetic analysis of stroke in the Japanese. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  54. Inomata H, Liang YQ, Yanai K, Isobe M,Kato N. Unraveling genetic susceptibility by the construction of eight consomic strains derived from the stroke-prone spontaneously hypertensive rat. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  55. Manabe N, Hoshino A, Liang Y-Q, Goto TKato N, Yamamoto K. Quantum dots conjugated with captoril while remained effective in vivo. 2nd International Conference on Advanced Materials and Nanotechnology, Queenstown, February, 2005.

III. 学術集会発表−国内学会・研究会

     
  1. 加藤規弘. ゲノム医療の国際連携と我が国の取り組み. 日本遺伝子診療学会:遺伝子診断・検査技術推進フォーラム 公開シンポジウム2016, 東京, 12月, 2016.
  2.  
  3. 加藤規弘. 国内外のバイオバンクの動向やNCBNの取組みについて. 第22回日本薬剤疫学会, 京都, 11月, 2016.
  4.  
  5. 島貫秀之、池田仁子、西本寛、若尾文彦、平松治彦、大塚文之、東山綾、高田彰、永井秀明、波多野賢二、松村亮、菊池嘉、秋山純一、廣井透雄、美代賢吾、野口貴史、渡辺浩、武田美江、岩田悟、峯有佳、渡邉裕司、三上礼子、加藤規弘. ナショナルセンター・バイオバンクネットワークのカタログデータベースの現状とこれから. 第36回医療情報学連合大会, 横浜, 11月, 2016.
  6.  
  7. 竹内史比古、清水華、加藤規弘. ゲノムワイド関連解析とエピゲノム解析による高血圧の機序解明. 第39回日本高血圧学会総会, 仙台, 10月, 2016.
  8.  
  9. 清水華、竹内史比古、磯野正人、秋山康一、梁一強、加藤規弘. 高血圧自然発症ラットの脳における、食塩負荷に伴うエピジェネティック変化. 第39回日本高血圧学会総会, 仙台, 10月, 2016.
  10.  
  11. 清水華、竹内史比古、磯野正人、秋山康一、梁一強、加藤規弘. 高血圧自然発症ラットの肝臓における、デキサメタゾン投与に伴うエピジェネティック変化. 第39回日本高血圧学会総会, 仙台, 10月, 2016.
  12.  
  13. 加藤規弘. 高血圧および関連疾患のゲノム研究. 第39回日本高血圧学会総会, 仙台, 10月, 2016.
  14.  
  15. 加藤規弘. 高血圧等の生活習慣病のゲノム/エピゲノム解析. 第4回低酸素研究会, 東京, 7月, 2016.
  16.  
  17. 大澤春彦、田原康玄、川村良一、塚田晃子、伊賀瀬道也、大橋順、山田亮、高田康徳、川本龍一、斉藤功、大沼裕、小原克彦、谷川武、大八木保政、山田一哉、加藤規弘、三木哲郎. レジスチン遺伝子プロモーターSNPとは独立して、新たな機能的SNPとして3’のrs1423096とrs10401670を同定した. 第59回日本糖尿病学会年次学術集会. 京都. 5月. 2016
  18.  
  19. 島貫秀之、佐藤泉美、田中康博、新保卓郎、西本寛、若尾文彦、原口亮、大塚文之、東山綾、高田彰、永井秀明、波多野賢二、松村亮、菊池嘉、日ノ下文彦、廣井透雄、美代賢吾、小塚和人、渡辺浩、岩田悟、丹藤昌治、望月修一、加藤規弘. ナショナルセンター・バイオバンクネットワークのカタログデータベースシステム構築. 第35回医療情報学連合大会, 沖縄, 11月, 2015.
  20.  
  21. 竹内史比古、磯野正人、梁一強、秋山康一、加藤規弘. 6クラスの降圧剤間での、ラットにおける心肥大抑制と遺伝子発現変動の比較:続報. 第51回高血圧関連疾患モデル学会総会, 大阪, 10月, 2015.
  22.  
  23. 竹内史比古、磯野正人、梁一強、秋山康一、加藤規弘. 3種のレニン–アンジオテンシン系関連降圧剤間での、ラットにおける降圧効果と腎臓での遺伝子発現変動の比較. 第51回高血圧関連疾患モデル学会総会, 大阪, 10月, 2015.
  24.  
  25. 梁一強、秋山康一、磯野正人、竹内史比古、加藤規弘. ラット染色体1番上の、心血管合併症遺伝子座の同定とその病態機序の探究.第51回高血圧関連疾患モデル学会総会, 大阪, 10月, 2015.
  26.  
  27. 梁一強、磯野正人、秋山康一、岡村匡史、竹内史比古、加藤規弘. ヒトcholesteryl ester transfer proteinのトランスジェニックラットにおける肝臓での脂質代謝解析. 第51回高血圧関連疾患モデル学会総会, 大阪, 10月, 2015.
  28.  
  29. 加藤規弘. 人種横断的ゲノムワイド関連解析による、新規の高血圧関連遺伝子座の同定とDNAメチル化の役割の推定:iGEN-BP国際共同研究での知見. 第38回日本高血圧学会総会, 松山, 10月, 2015.
  30. 竹内史比古、勝谷友宏、木村亮介、並河徹、大久保孝義、田原康玄、山本健、横田充弘、SAW, Woei-Yuh、TEO, Yik-Ying、加藤規弘. 日本人の精密な遺伝的構造の検討:アジア人の中での遺伝的由来及び遺伝的差異の起源の推定. 第60回日本人類遺伝学会. 東京, 10月, 2015.
  31. Woei-Yuh Saw, Xuanyao Liu, Chiea-Chuen Khor, 竹内史比古, 勝谷友宏, 木村亮介, 並河徹, 大久保孝義, 田原康玄, 山本健, 横田充弘, Yik-Ying Teo, 加藤規弘. Mapping the genetic diversity of HLA haplotypes in the Japanese populations. 第60回日本人類遺伝学会. 東京, 10月, 2015.
  32. Yik-Ying Teo for the Asian Diversity Project Group. Characterising private and shared signatures of positive selection in 37 Asian populations. 第60回日本人類遺伝学会. 東京, 10月, 2015.
  33. 坂井亜衣、帰山沙織、古谷真知、中屋隆裕、山田実夏、市川麻衣、佐藤さつき、今川美智子、山本勝司、藤井美紀、銭丸康夫、鈴木仁弥、牧野耕和、石塚 全、加藤規弘、此下忠志. アンジオテンシンII分解酵素、ENPEP遺伝子型と糖尿病性腎症の関連解析. 第38回日本高血圧学会総会, 松山, 10月, 2015.
  34. 竹内史比古、勝谷友宏、木村亮介、並河徹、大久保孝義、田原康玄、山本健、横田充弘、SAW, Woei-Yuh、TEO, Yik-Ying、加藤規弘. 日本人の精密な遺伝的構造の検討:アジア人の中での遺伝的由来及び遺伝的差異の起源の推定. 東京, 8月, 2015.
  35. 大澤春彦、田原康玄、川村良一、伊賀瀬道也、塚田晃子、高田康徳、川本龍一、斉藤功、大沼裕、小原克彦、谷川武、山田一哉、加藤規弘、三木哲郎. 全ゲノム関連解析により、血中レジスチンを規定する新たな機能的SNPとしてrs1423096とrs10401670を同定した. 第58回日本糖尿病学会年次学術集会. 下関. 5月. 2015.
  36. Sugiyama K, Sasano T, Tamura N, Okamura T,Kato N, Isobe M, Tetsushi Furukawa. Oxidative Stress Induced Ventricular Arrhythmias and Impaired Cardiac Function in Nos1ap Deleted Mice. 第79回日本循環器学会学術集会. 大阪. 4月. 2015.
  37. 磯野正人、梁一強、秋山康一、竹内. 史比古、加藤規弘. 降圧、心肥大抑制と遺伝子発現変動に関する、6クラスの降圧剤間での比較. 第50回高血圧関連疾患モデル学会総会, 和歌山, 12月, 2014.
  38. 坂井亜衣、中屋隆裕、山本勝司、山田実夏、市川麻衣、今川美智子、牧野耕和、藤井美紀、鈴木仁弥、石塚全、シャギデジャ ムードレイ、加藤規弘、此下忠志. ENPEP(angiotensinase A)遺伝子多型と高血圧症の相関解析. 第37回日本高血圧学会総会, 横浜, 10月, 2014.
  39. 梁一強、Nitish Mehta、秋山康一、磯野正人、加藤規弘. ラット染色体1番における、心血管合併症遺伝子座の多面的探索. 第37回日本高血圧学会総会, 横浜, 10月, 2014.
  40. 磯野正人、竹内史比古、山本健、横田充弘、勝谷友宏、秋山康一、加藤規弘. 東アジア人での遺伝的関連に関する、血圧と冠動脈疾患の間の不均一性. 第37回日本高血圧学会総会, 横浜, 10月, 2014.
  41. 秋山康一、梁一強、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統での腎臓mRNA発現解析を用いた高血圧感受性遺伝子の探索. 第36回日本高血圧学会総会, 大阪, 10月, 2013.
  42. 秋山康一、梁一強、磯野正人、加藤規弘. ヒトGWASで同定された脂質関連遺伝子のラット高脂肪食負荷における病態的意義の探究. 第36回日本高血圧学会総会, 大阪, 10月, 2013.
  43. 梁一強、秋山康一、磯野正人、岡村匡史、加藤規弘. ヒトcholesteryl ester transfer proteinの高血圧ラットへの遺伝子導入と代謝関連形質に対する影響の評価:続報. 第36回日本高血圧学会総会, 大阪, 10月, 2013.
  44. 梁一強、秋山康一、磯野正人、加藤規弘. ラット染色体1番における、血圧とは独立した心血管合併症遺伝子座の同定. 第36回日本高血圧学会総会, 大阪, 10月, 2013.
  45. 加藤規弘. ゲノムワイドから遺伝子機能解析への展開に係る見通し. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013       
  46. 秋山康一、梁一強、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統での腎臓mRNA発現解析を用いた高血圧感受性遺伝子の探索. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013.
  47. 秋山康一、梁一強、磯野正人、加藤規弘. ヒトGWASで同定された脂質関連遺伝子のラット高脂肪食負荷における病態的意義の探究. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013.
  48. 梁一強、秋山康一、磯野正人、岡村匡史、加藤規弘. ヒトcholesteryl ester transfer proteinの高血圧ラットへの遺伝子導入と代謝関連形質に対する影響の評価:続報. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013.
  49. 梁一強、秋山康一、芹澤昌邦、尾留川直子、宮岸真、下川和郎、磯野正人、加藤規弘. デキサメサゾン負荷に伴う遺伝子発現変動に関する、in vivoとin vitroの統合的解析. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013.
  50. 梁一強、秋山康一、磯野正人、加藤規弘. ラット染色体1番における、血圧とは独立した心血管合併症遺伝子座の同定. 第49回高血圧関連疾患モデル学会総会, 東京, 9月, 2013.
  51. 加藤規弘. 高血圧関連疾患のゲノム解析と展望. 島根大学高齢者難治性疾患予防研究 公開講演会. 出雲, 2月, 2013.
  52. 加藤規弘. 高血圧関連疾患のゲノム解析と展望. 動脈硬化Update2012, 東京, 9月, 2012.
  53. 秋山康一、梁一強、磯野正人、竹内史比古、加藤規弘. 高血圧自然発症ラット(SHR)系統を用いた、遺伝的血圧制御における中和的な遺伝子間相互作用の同定. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  54. 秋山康一、梁一強、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統を用いた、高脂肪食負荷時の脂質制御におけるヒト脂質関連遺伝子群及びメチル化機序の関与の検討. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  55. 梁一強、秋山康一、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統における心肥大遺伝子の探索:Endonuclease G遺伝子の確証と新規遺伝子座の同定. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  56. 梁一強、秋山康一、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統での、動脈硬化の多面的効果に関わる遺伝的機序の探索:血圧遺伝子座SHR-Bp4-1〜Bp4-3の同定. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  57. 梁一強、秋山康一、磯野正人、加藤規弘. 高血圧自然発症ラット(SHR)系統における高コレステロール血症責任遺伝子の探索:コレステロール遺伝子座TC15-1及びTC15-2の同定. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  58. 梁一強、秋山康一、磯野正人、岡村匡史、加藤規弘. ヒトcholesteryl ester transfer proteinの高血圧ラットへの遺伝子導入と代謝関連形質に対する影響の評価:第1報. 第35回日本高血圧学会総会, 名古屋, 9月, 2012.
  59. 青山千賀子, 加藤規弘, 小川佳宏, 河内正治. 当院における術前の抗血小板薬休薬と術後の動脈血栓性合併症発症の実態報告. 第34回日本臨床麻酔学会, 東京, 6月, 2012.
  60. 加藤規弘. 高血圧関連疾患のゲノム解析と展望. 第49回日本臨床分子医学会学術集会, 京都, 4月, 2012.
  61. 加藤規弘. Common diseaseの遺伝子マッピング:成果と課題. 東京大学22世紀医療センターセミナー, 東京, 2月, 2012.
  62. 加藤規弘. 高血圧のゲノムワイド関連解析と展望. 第8回京都レニンアルドステロンフォーラム, 京都, 1月, 2012.
  63. 加藤規弘. Pathogenesis of Primary Aldosteronism. Primary Aldosteronism Symposium 2011, 東京, 12月, 2011.
  64. 青山千賀子, 加藤規弘, 小川佳宏, 志賀由佳, 河内正治. 当院での術前の抗血小板薬休薬と術後血栓性合併症の実態報告. 第31回日本臨床麻酔学会, 沖縄, 11月, 2011.
  65. 加藤規弘. 高血圧のゲノムワイド関連解析と展望. 第48回日本臨床生理学会総会ランチョンセミナー, 東京, 11月, 2011.
  66. 加藤規弘, CAGE network. 全ゲノム関連解析による、東アジア人での高血圧関連遺伝子の探索:新規メカニズムと人種特異性の同定. 第34回日本高血圧学会総会, 宇都宮, 10月, 2011.
  67. 此下忠志, 加藤規弘, 木村朋子, 藤井美紀, 牧野耕和, 若原成行, 宮森勇. レニン-アンジオテンシン系(RAS)遺伝子型は同系抑制薬の効果を予測し得るか? -RASファルマコジェノミクスのシステマティックレビュー-. 第34回日本高血圧学会総会, 宇都宮, 10月, 2011.
  68. 加藤規弘, 竹内史比古, 山本健, 磯野正人, 勝谷友宏, 杉山卓郎, 並河徹, 藤岡晨宏, 大中佳三, 家森幸男, 山口修平, 小林祥泰, 高柳涼一, 荻原俊男. 日本人での大規模追試研究による、7つの候補遺伝子と血圧値/高血圧との関連の検討. 第34回日本高血圧学会総会, 宇都宮, 10月, 2011.
  69. 此下忠志, 加藤規弘, 宮森勇. 網羅的発現遺伝子解析により抽出された高血圧特異的遺伝子クラスター -高血圧とア ンジオテンシンII消去系遺伝子群発現低下との関連-. 第34回日本高血圧学会総会, 宇都宮, 10月, 2011.
  70. 加藤規弘. 日本人にみられる高血圧関連遺伝子多型. 第51回新潟高血圧談話会, 新潟, 7月, 2011.
  71. 加藤規弘. 高血圧の遺伝子解析の現状. 第73回東京心臓の会, 東京, 6月, 2011.
  72. 此下忠志、加藤規弘、宮森 勇. 網羅的解析による高血圧特異的発現遺伝子の抽出-RAS抑制系遺伝子群の意義. 第84回日本内分泌学会総会, 神戸, 4月, 2011.
  73. 加藤規弘. 動脈硬化性疾患に対する予防戦略. 第81回日本衛生学会学術総会, 東京, 3月, 2011.
  74. 加藤規弘. 世界の稀少疾患対策の動向. 第14回日本内分泌病理学会学術総会, 京都, 10月, 2010.
  75. 竹内史比古, 並河徹, 磯野正人, 勝谷友宏, 杉山卓郎, 山口修平, 小林祥泰, 家森幸男, 荻原俊男, 加藤規弘. 日本人において7つの新規遺伝子座が血圧値および高血圧と関連している. 第33回日本高血圧学会総会, 福岡, 10月, 2010.
  76. 加藤規弘. Post-GWAS時代における高血圧研究の世界的潮流と我が国からの提言. 第33回日本高血圧学会総会, 福岡, 10月, 2010.
  77. 竹内史比古, 加藤規弘. 遺伝子型間での量的形質の異分散性を活用した精密マッピング. 第55回日本人類遺伝学会, 大宮, 10月, 2010.
  78. 加藤規弘. 「統合的生命システム実証学」としてのゲノム疫学研究. 第80回日本衛生学会総会シンポジウム4「生活習慣病を標的とした分子疫学コホート研究の展望」, 仙台, 5月, 2010.
  79. 此下忠志, 加藤規弘, 高橋芳徳, 水野真一, 木村朋子, 藤井美紀, 牧野耕和, 荒川健一郎, 若原成行, 居軒 功, 宮森 勇、G-DOC Study Investigators. 網羅的解析による糖尿病腎症特異的発現遺伝子の抽出-Insulin Regulated Aminopeptidase (IRAP/AT4)の発現低下. 第53回日本糖尿病学会年次学術集会, 岡山, 5月, 2010.
  80. 加藤規弘, 梁一強, Zaidi Ali, 竹内史比古. 劇症型脳卒中易発症モデルラットの作成とポジショナルクローニング. 第32回日本高血圧学会総会, 大津, 10月, 2009.
  81. 此下忠志, 加藤規弘, 水野真一, 本村 誠, 青山千賀子, 木村朋子, 藤井美紀, 牧野耕和, 荒川健一郎, 若原成行, 居軒 功, Sebastien Fuchs, Florence Pinet, 宮森 勇、G-DOC Study Investigators. アンジオテンシン遮断薬responder決定因子としてのレニンアンジオテンシン系遺伝子. 第32回日本高血圧学会総会, 大津, 10月, 2009.
  82. 竹内史比古, 並河徹, 磯野正人, 勝谷友宏, 杉山卓郎, 山口修平, 小林祥泰, 家森幸男, 荻原俊男, 加藤規弘日本人の身長に影響する遺伝子多型の検証. 第54回日本人類遺伝学会, 東京, 9月, 2009.
  83. 加藤規弘. SHR/SHRSPを用いた分子薬理学の展望. 第45回高血圧関連疾患モデル学会学術総会, 東京, 9月, 2009.
  84. 弥富寿麻子, 岡野美江, 加賀朋子, 目﨑悦子, 田中めぐみ, 髙嶋美和, 橋本千草, 堀愛, 小林信之, 加藤規弘. 国立国際医療センターでの臨床研究コーディネーター(MRC)による臨床研究支援の試み. 第9回CRCと臨床試験のあり方を考える会議 2009, 横浜, 9月, 2009.
  85. 此下忠志, 加藤規弘, 牧野耕和, Sebastien Fuchs, Florence Pinet,宮森 勇, G-DOC Study Investigators. レニン遺伝子多型C-5312Tはアンジオテンシン遮断薬の降圧効果に影響する. 第52回日本腎臓学会, 横浜, 6月, 2009.
  86. 竹内史比古, 山本健, 藤澤智巳, 中島英太郎, 大中佳三, 池上博司, 杉山卓郎, 勝谷友宏, 宮岸真, 中島直樹, 名和田新, 中村二郎, 古野純典, 高柳涼一, 加藤規弘. 550Kアレイを用いた日本人2型糖尿病のGenome-Wide Association Studyと遺伝的効果の検証. 第52回日本糖尿病学会年次学術集会, 大阪, 5月, 2009.
  87. 此下忠志, 加藤規弘, 水野真一, 本村 誠, 青山千賀子, 木村朋子, 藤井美紀, 牧野耕和, 荒川健一郎, 若原成行, 居軒 功, Sebastien Fuchs, Florence Pinet, 宮森 勇、G-DOC Study Investigators. アンジオテンシン遮断薬responder決定因子としてのレニンアンジオテンシン系遺伝子と糖尿病. 第52回日本糖尿病学会年次学術集会, 大阪, 5月, 2009.
  88. 加藤規弘, 竹内史比古, 芹澤昌邦, 並河徹, 杉山卓郎, 勝谷友宏, 大久保孝義, 山口修平, 今井潤, 小林祥泰. Genome-Wide Association Studyによるラクナ梗塞と高血圧の感受性遺伝子探索. 第31回日本高血圧学会総会, 札幌, 10月, 2008
  89. 尾留川直子, 梁一強, 王涛, 張燕, 加藤規弘. SHRSP由来のサブコンジェニッック系統を用いた腎障害QTLのポジショナルクローニング. 第31回日本高血圧学会総会, 札幌, 10月, 2008.
  90. Zhang Y, Makaya M, Kastriratne A, Wang T, Miyagishi M, de Silva J, Wickremasinghe AR, Kato N. Type 2 Diabetes is associated with decreased plasma adiponectin levels independently of insulin resistance in South Asians. 第31回日本高血圧学会総会, 札幌, 10月, 2008.
  91. Wang T, Liang Y-Q, Zhang Y, Birukawa N,Kato N. Detection of a rat chromosome 4 region that influences blood pressure using a combination approach. 第31回日本高血圧学会総会, 札幌, 10月, 2008.
  92. Wang T, Liang Y-Q, Zhang Y, Birukawa N, Zhang Y.Kato N. Comprehensive evaluation of gene expression profile induced by six antihypertensive drugs on three end-organs. 第31回日本高血圧学会総会, 札幌, 10月, 2008.
  93. 此下忠志, 木村朋子, 藤井美紀, 牧野耕和, 若原成行, 居軒功, 宮森勇, 加藤規弘, Sebastien Fuchs. 糖尿病性腎症におけるレニン-アンジオテンシン系. 第20回日本糖尿病性腎症研究会, 東京, 12月, 2008.
  94. 此下忠志, 加藤規弘, 牧野耕和, 宮森勇. DNAチップを用いた糖尿病性腎症発現遺伝子の網羅的解析. 第77回北陸糖尿病集談会, 金沢, 12月, 2008.
  95. 此下忠志, 加藤規弘, 水野真一, 本村誠, 青山千賀子, 木村朋子, 牧野耕和, 若原成行, Sebastien Fuch, Florence Pinet, 宮森 勇. アンジオテンシン遮断薬レスポンダー決定因子-レニンアンジオテンシン系遺伝子と糖尿病-. 第76回北陸糖尿病集談会, 金沢, 7月, 2008.
  96. 此下忠志, 牧野耕和, 若原成行, 加藤規弘, 宮森勇. メタボリックシンドロームにおける循環系・組織レニン-アンジオテンシン系亢進. 第51回日本糖尿病学会, 東京, 5月, 2008.
  97. 眞茅みゆき, 三田村昌泰, 笠原茂, 古殿次郎, 上村直実, 加藤規弘. 臨床研究の推進を目的とした臨床研究レジストリおよび臨床データブックの開発と実用. 第9回日本医療情報学会学術大会, 横浜, 11月, 2008.
  98. 岡野美江, 眞茅みゆき, 加藤規弘. 遺伝情報をも対象とした臨床研究における臨床研究コーディネーターの役割. 第7回日本遺伝看護学会, 東京, 9月, 2008.
  99. 田邉真紀人、成瀬光栄、鈴木知子、Zheng-pei Zeng、加藤規弘、岡嶋泰一郎. 中国における肥満症・メタホリックシントロームの実態調査(第2報). 第16回西日本肥満研究会, 宮崎, 7月, 2008.
  100. 眞茅みゆき, 岩嶋義雄, 加藤規弘. 専門医療機関受診者におけるリスクの重積した非メタボリックシンドローム(MS)症例とMS症例の心血管イベント発生率の比較. 第44回日本循環器予防学会・日本循環器管理研究協議会総会, 秋田, 5月, 2008.
  101. 加賀朋子, 今田香, 川路美子, 立入朋子, 目崎悦子, 眞茅みゆき, 上村直実, 加藤規弘. 医師主導型臨床研究を支援する臨床研究コーディネーターの役割:国立国際医療センターでの取り組み. 第72回日本循環器学会総会, 福岡, 3月, 2008.
  102. 加藤規弘, ミレニアムプロジェクト高血圧コンソーシアム. 高密度SNP association studyによる高血圧感受性遺伝子の同定. 第30回日本高血圧学会総会, 那覇, 10月, 2007.
  103. 加藤規弘, 梁一強, 落合義徳, 尾留川直子, 芹澤昌邦, 眞茅みゆき. SHRをモデルとしたメタボリック・シンドローム関連形質の分断化とポジショナル・クローニング. 第30回日本高血圧学会総会, 那覇, 10月, 2007.
  104. 眞茅みゆき, 藤岡晨宏, 勝谷友宏, 荻原俊男, 家森幸男, 加藤規弘. コレステロール逆転送系に関連する14遺伝子と脂質代謝との関連:高血圧罹患の有無と一般集団中での遺伝的効果の検証. 第30回日本高血圧学会総会, 那覇, 10月, 2007.
  105. 河原申弥, 富樫廣子, Subrina Jesmin, Sohel Zaedi, 山口拓, 吉岡充弘, 加藤規弘. エンドセリン受容体遮断はSHRSP大脳皮質における脳血流低下を改善する. 第41回高血圧関連疾患モデル学会学術総会, 大阪, 9月, 2007.
  106. Subrina Jesmin, 富樫廣子, 河原申弥, Sohel Zaedi, 下條信武, 山口直人, 宮内孝, 加藤規弘. Normalization of impairment in VEGF signaling, coronary collateral development and cardiac function in early diabetic rat heart by dual endothelin antagonism. 第41回高血圧関連疾患モデル学会学術総会, 大阪, 9月, 2007.
  107. 中林一彦, 藤本崇弘, 馬場賀, 小柳緑, 顧寧, 土井佳子, 加藤規弘,笹月健彦, 白澤専二. Towards elucidating the transcription network regulated by a novel immune-related transcription factor ZFAT. 第52回日本人類遺伝学会, 9月, 2007.
  108. Serizawa M, Yanai K, Nabika T, Inomata H, Ochiai Y, Makaya M, Kobayashi S, Kato N. Genetic signature for the prevention of stroke in the Japanese population. 第71回日本循環器学会学術集会, 神戸, 3月, 2007.
  109. Ochiai Y, Kohara Y, Inomata H, Liang Y-Q, Serizawa M, Yanai K,Kato N. Unraveling genetic susceptibility by constructing 14 consomic strains derived from the spontaneously hypertensive rat strains. 第71回日本循環器学会学術集会, 神戸, 3月, 2007.
  110. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T,Kato N. Evaluation of 14 genes involved in reverse cholesterol transport in the Japanese general population. 第71回日本循環器学会学術集会, 神戸, 3月, 2007.
  111. 柳内和幸, 柳内圭子, 芹澤昌邦, 小池淑子, 落合義徳, 加藤規弘. ゲノムスケールでの転写因子標的配列の系統的な同定法の開発. 日本分子生物学会2006フォーラム, 名古屋, 12月, 2006.
  112. 芹澤昌邦, 柳内和幸, 柳内圭子, 小池淑子, 加藤規弘. ラットゲノムからのグルココルチコイド受容体結合配列の系統的な同定と解析. 日本分子生物学会2006フォーラム, 名古屋, 12月, 2006.
  113. 柳内圭子, 柳内和幸, 小池淑子, 芹澤昌邦, 加藤規弘. ヒトゲノムからのエストロゲン受容体結合配列の系統的な同定と解析. 日本分子生物学会2006フォーラム, 名古屋, 12月, 2006.
  114. 藤岡晨宏, 眞茅みゆき, 加藤規弘. 尼崎市民健康開発センターの検診受診者における高血圧の発症頻度および発症関連要因の検討. 第65回日本公衆衛生学会総会、富山, 10月, 2006.
  115. 落合義徳, 梁一強, 猪又兵衛, 芹澤昌邦, 柳内和幸, 加藤規弘, 矢崎義雄. レニン-アンジオテンシン-アルドステロン系遺伝子群の臓器および外的刺激に特異的な発現変動. 第14回分子高血圧研究会, 東京, 10月, 2005.
  116. 猪又兵衛, 梁一強, 落合義徳, 芹澤昌邦, 磯部光章, ,柳内和幸, 加藤規弘. コンジェニックラットにおけるQTLの検証とfine mappingのための戦略的アプローチ. 第41回高血圧関連疾患モデル学会学術総会, 札幌, 9月, 2005.
  117. 落合義徳, 梁一強, 猪又兵衛, 芹澤昌邦, 柳内和幸, 加藤規弘. DNAマイクロアレイ法を用いた降圧剤応答性遺伝子群の検出—ファーマコゲノミクスへの展開. 第41回高血圧関連疾患モデル学会学術総会, 札幌, 9月, 2005.
  118. 加藤規弘, 柳内和幸, 竹内史比古, 猪又兵衛, 眞茅みゆき, 柳内圭子, 長野忍, 並河徹, 勝谷友宏, 藤岡晨宏, 安田和基, 家森幸男, 小林祥泰, 荻原俊男, 矢崎義雄. 動脈硬化性疾患に関する複合的かつ大規模な候補遺伝子解析. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  119. 猪又兵衛, 梁一強, 落合義徳, 芹澤昌邦, 磯部光章, 柳内和幸, 加藤規弘. SHRSP由来の8コンソミック系統を用いた、高血圧関連疾患の組織的な遺伝子解析. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  120. 猪又兵衛, 梁一強, 落合義徳, 芹澤昌邦, 磯部光章, 柳内和幸, 加藤規弘. コンジェニックラットにおけるQTLの検証とfine mappingのための戦略的アプローチ. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  121. 落合義徳, 梁一強, 猪又兵衛, 芹澤昌邦, 柳内和幸, 加藤規弘. DNAマイクロアレイ法を用いた降圧剤応答性遺伝子群の検出:ファーマコゲノミクスへの展開. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  122. 落合義徳, 梁一強, 猪又兵衛, 芹澤昌邦, 柳内和幸, 加藤規弘. レニンーアンジオテンシン系遺伝子の網羅的発現解析. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  123. 柳内和幸, 長野忍, 芹澤昌邦, 小池淑子, 落合義徳, 柳内圭子 竹内史比古, 加藤規弘. 代謝性疾患の個別化医療に向けた統合データベース構築:JMDBase. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  124. 柳内和幸, 並河徹, 竹内史比古, 猪又兵衛, 小林祥泰, 加藤規弘. 2つの新規な脳卒中感受性遺伝子—PDE4DとALOX5AP—の脳硬塞の病型分類を考慮した日本人での評価. 第28回日本高血圧学会総会, 旭川, 9月, 2005.
  125. 真鍋法義、星野昭芳、梁一強、後藤知将、加藤規弘、山本健二. Quantum dotsと薬剤の結合によるn vivoでの効果. 日本薬学会第125年会, 東京, 3月, 2005.